摘要
目的探讨经鼻高流量湿化氧疗治疗急性低氧性呼吸衰竭的临床疗效。方法将82例急性低氧性呼吸衰竭患者按入院顺序分为两组,每组41例。实验组行经鼻高流量湿化氧疗治疗,对照组行无创正压通气治疗,观察2h。比较两组患者的临床疗效、治疗2h后口腔舒适度评分,以及治疗前及治疗2h后的血气分析指标(二氧化碳分压、血氧张力、氧饱和度、酸碱度)变化。结果实验组治疗总有效率及口腔舒适度评分显著高于对照组(P<0.01)。治疗2h后两组患者二氧化碳分压较治疗前显著降低(P<0.01),血氧张力、氧饱和度较治疗前显著升高(P<0.01),实验组显著优于对照组(P<0.01);实验组患者口腔舒适评分明显高于对照组(P<0.01)。结论经鼻高流量湿化氧疗治疗急性低氧性呼吸衰竭患者临床疗效显著,且能提高患者的口腔舒适度。
Objective To study the therapeutic effect of HHFNC on acute hypoxic respiratory failure.Methods 82 patients with acute hypoxic respiratory failure were randomly divided into two groups according to the order of admission,with 41 patients in each group.The experimental group was treated with HHFNC,and the control group was treated with non-invasive positive pressure ventilation for 2 h.The clinical efficacy of the two groups of patients,the oral comfort score after 2 h of treatment,and the changes in blood gas analysis indicators(PaCO2,PaO2,SaO2,PH)before and 2 h after treatment of the two groups were compared.Results The total effective rate and oral comfort scores of the experimental group were significantly higher than those of the control group(P<0.01).PaCO2 was significantly lower in the two groups after treatment for 2 h(P<0.01),PaO2 and SaO2 were significantly higher than those before treatment(P<0.01),and the experimental group was significantly better than the control group(P<0.01).The experimenlal group was significantly higher than the control group.Conclusion The clinical efficacy of HHFNC for acute hypoxic respiratory failure is significant,and the patient's comfort is improved.
作者
李克
范永会
井鹏程
Li Ke;Fan Yonghui;Jing Pengcheng(Pingmei Shenma Medical Group General Hospital,Pingdingshan 467000,Henan,China)
出处
《临床心身疾病杂志》
CAS
2019年第3期141-142,155,共3页
Journal of Clinical Psychosomatic Diseases
基金
平顶山市科技攻关项目(编号150618207).
