摘要
目的探讨雾化吸入盐酸氨溴索治疗小儿肺炎的临床疗效。方法选取2017年5月~2018年2月我院88例小儿肺炎患儿。根据随机数字表法分为两组,对照组采取常规药物治疗,盐酸氨溴索组则采取常规药物加上雾化吸入盐酸氨溴索治疗。比较两组效果;咳嗽消失、肺部湿啰音消失、体温和呼吸频率恢复正常的时间、住院时间;治疗前后患儿肺功指标和血气指标;副反应。结果盐酸氨溴索组疗效为93.18%优于对照组的68.18%,差异有统计学意义(P<0.05)。治疗后盐酸氨溴索组肺功指标和血气指标FVC(L)、PEF(L/S)、PaO2(kPa)、PaCO2(kPa)分别是(3.71±1.31)L、(5.24±1.12)L/S、(12.64±2.52)kPa、(5.14±0.12)kPa,优于对照组(2.25±1.11)L、(4.55±1.02)L/S、(10.21±1.33)kPa、(5.14±0.12)kPa,差异有统计学意义(P<0.05)。盐酸氨溴索组咳嗽消失、肺部湿啰音消失、体温和呼吸频率恢复正常的时间、住院时间(4.11±1.01)d、(4.11±1.02)d、(1.43±0.55)d、(3.55±1.21)d、(5.13±0.22)d均短于对照组,差异有统计学意义(P<0.05)。盐酸氨溴索组不良反应和对照组比较无明显差异(P>0.05)。结论常规药物加上雾化吸入盐酸氨溴索治疗小儿肺炎的效果理想。
Objective To investigate the clinical efficacy of aerosol inhalation of ambroxol hydrochloride in the treatment of children with pneumonia. Methods 88 children with pediatric pneumonia in our hospital from May 2017 to February 2018 were selected. The patients were grouped according to the random number table. The control group was treated with conventional drugs, and the ambroxol hydrochloride group was treated with conventional drugs plus aerosol inhalation of ambroxol hydrochloride. The effects, the cough disappearance time, the wetness of the lungs disappearance time, the time of body temperature and respiratory rate returned to normal, and the hospital stay, the lung function index and blood gas index before and after treatment and side effects of the control group and the ambroxol hydrochloride group were compared. Results The efficacy of ambroxol hydrochloride group was 93.18%, which was better than that of the control group (68.18%). The difference was statistically significant (P<0.05). After treatment, the lung function index and blood gas indexes FVC(L), PEF(L/S), PaO2(kPa) and PaCO2(kPa) of the ambroxol hydrochloride group were (3.71±1.31)L,(5.24±1.12)L/S,(12.64±2.52)kPa and (5.14±0.12)kPa, respectively, which were better than (2.25±1.11)L,(4.55±1.02)L/S,(10.21±1.33)kPa and (5.14±0.12)kPa in the control group, and the difference was statistically significant (P<0.05). The cough disappearance time(4.11±1.01)d , the lungs wetness disappearance time(4.11±1.02)d, the time when the body temperature and respiratory rate returned to normal(1.43±0.55)d and(3.55±1.21)d, and the length of hospital stay(5.13±0.22)d in the ambroxol hydrochloride group was better than that of the control group, and the difference was statistically significant(P<0.05). There was no significant difference in the side reaction between ambroxol hydrochloride group and the control group(P>0.05). Conclusion Conventional drugs combined with aerosolized ambroxol hydrochloride are effective in the treatment of pediatric pneumon
作者
甘瀛
GAN Ying(Department of Pediatrics,Jiamusi Maternal and Child Health Hospital in Heilongjiang Province,Jiamusi 154002,China)
出处
《中国现代医生》
2019年第12期60-62,共3页
China Modern Doctor
关键词
雾化吸入
盐酸氨溴索
小儿肺炎
Erosol inhalation
Ambroxol hydrochloride
Pediatric pneumonia
