摘要
目的分析患者自控静脉镇痛(PCIA)纳布啡+舒芬太尼对全髋关节置换术(THA)患者Ramsay镇静评分、疼痛视觉模拟评分法(VAS)及镇痛效果的影响。方法选取2017年1-12月临汾市人民医院收治的72例行THA治疗的患者,均行PCIA,按照麻醉形式不同分为A组给予纳布啡,B组给予舒芬太尼,C组给予纳布啡+舒芬太尼,三组各24例。比较三组手术前后患者Ramsay镇静评分、VAS评分及镇痛效果。结果A组患者术后3、12、24 h时Ramsay镇静评分分别为(2.78±0.32)分、(2.59±0.40)分、(2.45±0.26)分,C组患者术后3、12、24 h时Ramsay镇静评分分别为(2.37±0.24)分、(2.01±0.15)分、(1.89±0.22)分,较B组同时间点的(3.07±0.58)分、(3.01±0.62)分、(2.73±0.47)分明显下降(F组间=6.83,P组间=0.01;F时点间=7.24,P组间<0.01;F组间·时点间=0.69,P组间·时点间=0.40)。B组患者术后3、12、24 h时VAS评分分别为(2.40±0.72)分、(1.98±0.57)分、(1.24±0.38)分,C组患者术后3、12、24 h时VAS评分分别为(2.35±0.75)分、(1.74±0.46)分、(1.18±0.26)分,较A组同时间点的(3.35±0.59)分、(3.18±0.46)分、(3.01±0.33)分明显下降(F组间=7.02,P组间<0.01;F时点间=5.42,P组间=0.02;F组间·时点间=0.39,P组间·时点间=0.68)。三组患者镇痛满意度的比较,差异有统计学意义(χ^2=7.66,P<0.05);其中,C组患者镇痛满意度(91.67%)较A组(58.33%)、B组(62.50%)明显升高(χ^2=5.44、4.25,均P<0.05)。结论PCIA纳布啡+舒芬太尼用于行THA治疗的患者镇静和镇痛效果确切,舒适性高,可有效减轻患者痛苦,故此具有确切的临床应用价值。
Objective To analyze the effects of nabuprofen combined with sufentanil on Ramsay sedation score, visual analogue scale (VAS) and analgesic effect in patients undergoing total hip arthroplasty (THA) for patient-controlled intravenous analgesia (PCIA). Methods From January 2017 to December 2017, 72 patients with THA in the Department of Orthopedics from the People's Hospital of Linfen were divided into three groups: A group was given nabuprofen, B group was given sufentanil, C group was given nabuprofen + sufentanil, with 24 cases in each group.Ramsay sedation score, VAS score and analgesic effect were compared among the three groups before and after operation. Results The Ramsay sedation scores of A group at 3, 12 and 24 hours after operation were (2.78±0.32)points,(2.59±0.40)points and (2.4±0.26)points, respectively, and the Ramsay sedation scores of C group at 3, 12 and 24 hours after operation were (2.37±0.24)points,(2.0±0.15)points,(1.89±0.22)points, respectively, which were decreased significantly compared with those of B group at the same time point [(3.07±0.58)points,(3.01±0.62)points and (2.73±0.47)points](Fbetween group=6.83, Pbetween group=0.01;Ftime point=7.24, Ptime point<0.01;Fbetween group·time point=0.69, Pbetween group·time point=0.40). The VAS scores of group B at 3, 12 and 24 hours after operation were (2.40±0.72)points,(1.98±0.57)points and (1.24±0.38)points, respectively, and the VAS scores of C group at 3, 12 and 24 hours after operation were (2.35±0.75)points,(1.74±0.46)points and (1.18±0.26)points, respectively, which were decreased significantly compared with those of A group at the same time point [(3.35±0.59)points,(3.18±0.46)points and (3.01±0.33)points](Fbetween group=7.02, Pbetween group<0.01;Ftime point=5.42, Ptime point=0.02;Fbetween group·time point=0.39, Pbetween group·time point=0.68). There was statistically significant difference among the three groups (χ^2=7.66, P<0.05). The analgesic satisfaction of C group (91.67%) was significantly higher than that of
作者
王志国
柏宁
李炜
Wang Zhiguo;Bo Ning;Li Wei(Department of Anesthesiology, the People's Hospital of Linfen, Linfen, Shanxi 041000, China)
出处
《中国基层医药》
CAS
2019年第9期1119-1122,共4页
Chinese Journal of Primary Medicine and Pharmacy
