摘要
目的 探讨双歧杆菌三联活菌辅助蓝光照射治疗新生儿黄疸的疗效分析。方法 将2016年8月—2018年8月在该院新生儿科治疗的90例新生儿黄疸患儿随机分为两组,对照组采用蓝光照射治疗,在此基础上观察组采用双歧杆菌三联活菌辅助治疗,比较两组患儿的胆红素水平、黄疸消退时间、临床疗效。结果 观察组治疗后1 d、3 d、5 d的经皮胆红素水平分别为(252.46±42.75)μmol/L、(207.68±34.83)μmol/L、(143.94±32.94)μmol/L明显低于对照组的(266.84±41.92)μmol/L、(239.77±38.48)μmol/L、(194.57±41.39)μmol/L(t=4.032,4.414,5.346,P<0.05);观察组黄疸消退时间为(3.74±0.53)d明显短于对照组的(5.25±0.39)d,而日均胆红素下降值为(24.31±5.46)μmol/L明显高于对照组的(15.27±5.68)μmol/L(t=4.303,4.987,P<0.05);观察组治疗有效率为97.78%,明显高于对照组的80.00%(χ~2=10.21,P<0.05);观察组腹泻、稀便、褐色便等不良反应发生率明显低于对照组(χ~2=11.34,P<0.05)。以上差异有统计学意义(P<0.05)。结论 双歧杆菌三联活菌辅助蓝光照射来治疗新生儿黄疸的疗效显著,更能有效促进胆红素分解,改善高胆红素血症,促进黄疸的快速消退,具有积极的临床意义。
Objective To investigate the efficacy of Bifidobacterium triple viable bacteria combined with blue light irradiation in the treatment of neonatal jaundice. Methods A total of 90 cases of neonatal jaundice treated in our hospital from August 2016 to August 2018 were randomly divided into two groups. The control group was treated with blue light irradiation. On this basis, the observation group was treated with Bifidobacterium triple live bacterium adjuvant therapy. The bilirubin level, jaundice subsidence time and clinical efficacy of the two groups were compared. Results The levels of transdermal bilirubin in the observation group were (252.46±42.75)μmol/L,(207.68±34.83)μmol/L,(143.94±32.94)μmol/L on the 1st, 3rd and 5th day after treatment, respectively, which were significantly lower than those in the control group (266.84±41.92)μmol/L,(239.77±38.48)μmol/L,(194.57±41.39)μmol/L,(P<0.05)(t=4.032,4.414,5.346, P<0.05). The astragalus regression time was (3.74±0.53) d in the observation group, which was significantly shorter than that in the control group (5.25±0.39) d. And the daily mean bilirubin decrease value was (24.31±5.46) micromol/L in the observation group, which was significantly higher than that in the control group (15.27±5.68)μmol/L (t=4.303,4.987, P<0.05). The effective rate in the observation group was 97.78%, which was significantly higher than that in the control group 80%(χ^2=10.21, P<0.05). The incidence of adverse reactions such as diarrhea, dilution and defecation in the observation group were significantly lower than that of the control group (χ^2=11.34, P<0.05). the difference was statistically significant.Conclusion Bifidobacterium triple viable bacteria combined with blue light irradiation is effective in the treatment of neonatal jaundice. It can effectively promote bilirubin decomposition, improve hyperbilirubinemia, and promote the rapid regression of jaundice. It has positive clinical significance.
作者
张静
魏向花
ZHANG Jing;WEI Xiang-hua(Department of Pediatrics,Beitun Hospital,the 10th Division of Xinjiang Production and Construction Corps,Beitun,Xinjiang,836099 China)
出处
《世界复合医学》
2019年第3期40-42,共3页
World Journal of Complex Medicine
关键词
新生儿黄疸
双歧杆菌三联活菌
蓝光照射
疗效分析
Neonatal jaundice
Bifidobacterium triple viable bacteria
Blue light irradiation
Efficacy analysis
