摘要
目的:初步比较冰水循环微波消融与常温水循环微波消融对消融灶形态的影响。方法:取离体猪肝脏共9个,重4.5～5.2 kg。每块肝脏在不同位置用常温水及冰水循环同时进行消融。根据循环水不同分为冰水冷循环组及常温水冷循环组。实验在不同消融功率(40、60、80 W)下分别进行不同消融时间(5、8、10 min)各1次。消融结束后,沿针道切开肝脏,测量消融灶的纵径(LD)、横径(TD)、前冲径(PD),计算类圆率(SR)。结果:冰水组在纵径上较常温组分别相对缩短13%、10%、12%、15%、11%、13%、8%、8%,而横径及前冲径无明显变化,而冰水组在类圆率上分别相对提高22%、21%、7%、14%、1%、1%、11%、5%、4%;另外,在相同功率下,短消融时间(5 min)时类圆率改善相对明显;而在相同消融时间下,低功率(40 W)时类圆率改善相对明显。结论:本研究初步提示,冰水冷循环微波消融可能可以通过缩短消融灶纵径提高类圆率,改善消融区域形态,尤其是在低功率短时间的情况下效果可能更好,但仍需进一步实验获得更为准确的结果。
Objective:To compare the effect of ice water cooled cycle microwave ablation and normal temperature water cooled cycle ablation on the morphology of ablation area. Methods Nine pieces of fresh isolated porcine livers,weighing 4.5-5.2 kg. The experiment was divided into ice water cooled cycle group and nomral temperature water cooled cycle group. Each liver was ablated with normal temperature water cycle and ice water cooled cycle at the same time,at different ablation power(40,60,80 W),with different duration(5,8,10 min). After ablation,the liver tissues were cut along the needle path. The longitudinal diameters(LD),transverse diameters(TD)and preshoot diameters(PD)of the ablation areas were measured,and the spherical ratios(SR)were calculated.Results:Descriptive approach was used for preliminary reporting. Compared with the normal temperature group,the LD of the ice water group was relatively shortened by 13%,10%,12%,15%,11%,13%,8%,8%,while the TD and PD were not obviously changed,so the SR was relatively increased by 22%,21%,7%,14%,1%,1%,11%,5%,4%. In addition,at the same power,the improvement of SR was more obvious in short duration time(5 min). While at the same duration time,the improvement of SR was more obvious at low power(40 W). Conclusion:This experiment preliminarily hints that microwave ablation with ice water cold cycle may increase the SR by shortening the LD of the ablation area,especially in the case of low power and short time. But further experiments are needed to obtain more accurate results.
作者
丁逸文
施海彬
孙良俊
陈奇峰
徐红豆
杨正强
Ding Yiwen;Shi Haibin;Sun Liangjun;Chen Qifeng;Xu Hongdou;Yang Zhengqiang(Department of Interventional Radiology, the First Affiliated Hospital of NMU, Nanjing 210029;ECO Corporation,Nanjing 210000;Department of Interventional Radiology, Sun Yat - sen University Cancer Center, Guangdong 510060;Department of Interventional Radiology, Cancer Hospital Chinese Academy of Medical Sciences, Beijing 100021, China)
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2019年第4期581-584,共4页
Journal of Nanjing Medical University(Natural Sciences)
基金
国家自然科学基金(81571777)
关键词
微波消融
冰水冷却循环
类圆率
microwave ablation
ice water cooled cycle
spherical ratio
