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孟鲁司特钠联合盐酸西替利嗪口服溶液治疗小儿咳嗽变异性哮喘的临床研究 被引量:42

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摘要 咳嗽变异性哮喘(cough variant asthma,CVA)是以慢性咳嗽为临床表现的特殊哮喘类型,存在气道高反应性,数据显示,18%~40%的儿童慢性咳嗽为CVA,主要由呼吸道感染所致,但由于其临床特异性不明显,易出现漏诊、误诊情况,延误治疗时机[1].糖皮质激素、支气管扩张剂等均是以往临床治疗CVA常用药物,虽有一定治疗效果,但易损伤患儿气管与组织功能,造成病情迁延难愈[2].盐酸西替利嗪口服溶液可有效降低气道高反应性,减轻或消除咳嗽症状.孟鲁司特钠作为白三烯受体拮抗药物,可有效减轻支气管痉挛症状,缓解气道炎性反应.本研究选取84例CVA患儿,从气道炎症反应方探究孟鲁司特钠联合盐酸西替利嗪口服溶液应用效果.现报告如下.
作者 王雅琴
出处 《中国药物与临床》 CAS 2019年第10期1652-1654,共3页 Chinese Remedies & Clinics
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