摘要
目的观察不同时机高压氧治疗对格拉斯哥昏迷量表(GCS)评分、改良Rankin量表(mRS)评分、Zarit照顾者负担量表(ZBI)评分的改善作用,为采取高压氧介入治疗重型颅脑外伤的时机提供临床依据。方法收集64例重型颅脑外伤患者,依据高压氧介入治疗的时机不同分为早期治疗组33例及晚期治疗组31例。早期治疗组于起病后7～30天内行高压氧治疗,晚期治疗组于起病后31～60天内行高压氧治疗。两组均治疗1个月。比较两组起病时、3月、6月的GCS评分、mRS评分、ZBI评分。结果早期治疗组在3月、6月的GCS评分均较晚期治疗组高(P <0. 05);早期治疗组在3、6月的ZBI评分比晚期治疗组低;两组患者经高压氧介入治疗后GCS评分、ZBI评分在3月和6月时均较治疗前改善,差异具有统计学意义(P <0. 05)。早期治疗组的mRS评分≤2分的人数高于晚期治疗组,差异有统计学意义(P <0. 05)。结论早期高压氧介入治疗较晚期高压氧介入治疗更能改善患者在GCS、mRS、ZBI的评分。
Objective To observe the improved impact of hyperbaric oxygen therapy at different times on Glasgow Coma Scale( GCS) score,modified Rankin scale( mRS) score and Zarit caregiver burden scale( ZBI) score,in order to proved the clinical references for the timing of hyperbaric oxygen intervention for severe craniocerebral trauma.Methods Sixty-four patients with severe craniocerebral trauma were enrolled.According to the timing of hyperbaric oxygen intervention,33 patients were treated at the early stage and31 patients at the advanced stage.In the early treatment group,hyperbaric oxygen therapy was performed within 7 to 30 days after onset,and in the advanced treatment group,hyperbaric oxygen therapy was performed within 31 to 60 days after onset.Both groups were treated for 1 month.The GCS scores,mRS scores and ZBI scores at onset,and after 3 and 6 months of treatment were compared between the two groups.Results The GCS scores of the early treatment group were higher while the ZBI score was lower after 3 and 6 months of treatment than those in the advanced treatment group( P < 0. 05).After interventional therapy,the GCS score and ZBI score were all improved after 3 and 6 months in both groups( P < 0. 05).The number of patients with mRS score ≤ 2 in the early treatment group was more than that in the advanced treatment group( P < 0. 05).Conclusion Early hyperbaric oxygen intervention can improve the scores of GCS,mRS and ZBI in patients with severe craniocerebral trauma.
作者
秦晓洪
吴薇
陈胡萍
曾宪容
雷艳
翟培
QIN Xiao-hong;WU Wei;CHEN Hu-ping;ZENG Xian-rang;LEI Yan;ZHAI Pei(Southwest Medical University,Luzhou 646000,China;Hyperbaric Oxygen Treatment Center,Sichuan Academy of Medical Science & Sichuan People’s Hospital,Chengdu 610072,China;Department of Hyperbaric Oxygen,Sichuan Bayi Rehabilitation Center,Chengdu 610000,China)
出处
《实用医院临床杂志》
2019年第3期183-185,共3页
Practical Journal of Clinical Medicine
关键词
不同时机
高压氧治疗
颅脑外伤
Different times
Hyperbaric oxygen therapy
Traumatic brain injury
