摘要
目的分析石河子地区中青年(20～60岁)女性患者急性心肌梗死主要危险因素、临床表现、冠脉病变特点、救治及预后情况。方法收集医院2015-2017年住院中青年女性(20～60岁)急性ST段抬高心肌梗死患者51例(心梗组)和同期在医院住院并行冠状动脉造影检查且冠脉无狭窄的中青年女性179例(正常组)的临床资料。结果心梗组患者来自农牧团场比例更高,心梗组患者吸烟/被动吸烟、高盐高胆固醇饮食、高血压、糖尿病、血脂代谢异常及冠心病家族史者比例高于正常组,差异有统计学意义(P <0. 05); Logistic多因素分析显示高血压病史、糖尿病病史、血脂代谢异常史、空腹血糖、低密度脂蛋白胆固醇是心肌梗死患者的独立危险因素,高密度脂蛋白胆固醇是心肌梗死的保护因素。结论高血压、糖尿病、血脂代谢异常病史、空腹血糖、低密度脂蛋白胆固醇是石河子地区中青年女性患者急性心肌梗死的独立危险因素,高密度脂蛋白胆固醇是保护因素;本地区中青年女性急性ST段抬高性心肌梗死病变血管以单支和三支为主,梗塞血管多见于前降支。
Objective To analyze the main risk factors, clinical manifestations, characteristics of coronary artery lesions, treatment and prognosis of acute myocardial infarction in young and middle-aged women (20-60 years old) in Shihezi area. Methods The clinical data of 51 young and middle-aged women (20-60 years old) with acute ST-segment elevation myocardial infarction ( ST-segment elevation myocardial infarction group) admitted to hospital from 2015 to 2017 and 179 young and middle-aged women (normal group) admitted to hospital with coronary angiography without coronary artery stenosis at the same time were collected. Results The proportion of people from farming and pastoral areas was higher in the myocardial infarction group. The proportion of active or passive smoking, high salt and cholesterol diet, hypertension, diabetes mellitu s, dyslipidemia and family history of coronary heart disease in patients with myocardial infarction was higher than that in normal group ( P < 0. 0 5 ). Logistic multivariate analysis showed that hypertension, diabetes mellitus, dyslipidemia, fasting blood sugar and low density lipoprotein cholesterol were independent risk factors for myocardial infarction. High density lipoprotein cholesterol is a protective factor for myocardial infarction. Conclusion Hypertension, diabetes mellitus, history of abnormal lipid metabolism, fasting blood sugar and low density lipoprotein cholesterol are independent risk factors for acute myocardial infarction in young and middle-aged women in Shihezi area. High density lipoprotein cholesterol is a protective factor. Acute ST-segment elevation myocardial infarction in young and middle-aged women in this region is characterized by single and three vessels, and most of the infarcted vessels are in the anterior descending artery.
作者
瞿德涛
王忠
刘静
张修泽
郭辉芳
张艳芳
QU De-tao;WANG Zhong;LIU Jing(Department of Cardiovascular Medicine, First Affiliated Hospital of Medical College of Shihezi University, ShiheziCity, Xinjiang 832008, China)
出处
《临床合理用药杂志》
2019年第11期6-8,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
中青年女性
急性心肌梗死
危险因素
冠状动脉造影
Young and middle-aged women
Acute myocardial infarction
Risk factors
Coronary angiography
