摘要
目的:使用激光多普勒仪的二氧化碳分压单元,通过特定的数据处理,实现对经皮二氧化碳释放率(transcutaneous CO2emissing rate,TCER)的测量,以反映局部组织的能量代谢水平。方法:选择36名无明确诊断疾病的健康人作为受试者。使用二氧化碳分压单元测量8名受试者全身5个部位的经皮二氧化碳分压(transcutaneous carbon dioxide partial pressure,TcPCO_2),用MATLAB程序对线性分压曲线中最小值之后的一段曲线进行最小二乘法线性拟合,以拟合直线的斜率作为TCER,然后计算TcPCO_2、TCER的相对标准偏差并进行比较;测量6名受试者屏气前后的TcPCO_2,通过计算得到TCER值;测量22名受试者(12名男性、10名女性)肘部和腕部的TcPCO_2,通过计算得到TCER值。使用MATLAB软件、SPSS 22.0统计学软件对数据进行处理。结果:二氧化碳体积分数差的对数随时间呈线性变化。TcPCO_2、TCER的相对标准偏差分别为0.01±0.04、0.86±0.30,差异有显著性(P<0.01)。屏气前、后的TCER分别为(5.16±1.94)、(6.16±1.98)mmHg/s(1 mmHg=133.322 Pa),差异有显著性(P<0.01);肘部与腕部的总体TCER均值分别为(4.73±1.44)、(3.88±1.24)mmHg/s,差异有显著性(P<0.01);男性肘部与腕部的TCER分别为(4.94±1.50)、(3.55±1.28)mmHg/s,差异有显著性(P<0.01),女性肘部与腕部的TCER分别为(4.48±1.36)、(4.28±1.09)mm Hg/s,无显著性差异。结论:使用二氧化碳分压测量单元可以有效地测量TCER,从而对局部组织的能量代谢做出评估,该方法与以往经皮二氧化碳释放量(transcutaneous CO_2 emission,TCE)测量发现的规律类似,可弥补TCE测量的缺陷。
Objective To use the transcutaneous carbon dioxide partial pressure(TcPCO2)unit of laser Doppler instrument to measure and calculate transcutaneous CO2 emissing rate(TCER)by special data processing so as to reflect the energy metabolism of the local tissue.Methods Totally 36 healthy persons with no diseases diagnosed were seleted as the subjects,TcPCO2 unit was measured at five parts of the whole body in 8 subjects with a carbon dioxide pressure analyzer.A section of linear partial pressure curve after the minimum underwent least square fitting with MATLAB,and the slope of the fitted curve was used as TCER,then the relative standard deviations of TcPCO2 and TCER were calculated and compared.TCER of 6 subjects were measured and calculated before and after breath holding;TCERs at the elbow and wrist were measured and calculated in 22 subjects(12 men,10 women).MATLAB and SPSS 22.0 software was used for data processing.Results The carbon dioxide tension increased as negative exponent following the time.There was a very significant difference between relative standard deviation(RSD)of TcPCO2(0.01±0.04)and TCER(0.86±0.30)(P<0.01).The TCER before and after holding the breath were(5.16±1.94)mmHg/s(1 mmHg=133.322 Pa)and(6.16±1.98)mmHg/s respectively,with a significant increase(P<0.01).The overall mean value of TCER in the elbow and wrist were(4.73±1.44)mmHg/s and(3.88±1.24)mmHg/s respectively,which had significant difference(P<0.01).Men and women compared respectively,the TCER in elbow(4.94±1.50)mmHg/s of male group was significantly higher than that in the wrist(3.55±1.28)mmHg/s(P<0.01).There was no a significant difference between TCER in the elbow(4.48±1.36)mmHg/s and wrist(4.28±1.09)mmHg/s of the female group.Conclusion The use of a carbon dioxide partial pressure measurement unit can effectively measure TCER,thereby evaluating the energy metabolism of local tissues.This method is similar to the laws discovered by TCE measurement in the past,and can replace and make up for TCE measurement defects.
作者
李朝政
古菲菲
王燕平
赵朋娜
张维波
LI Chao-zheng;GU Fei-fei;WANG Yan-ping;ZHAO Peng-na;ZHANG Wei-bo(ENNova Health Science and Technology Co.,Ltd.,Langfang 065001,Hebei Province,China;School of Acupuncture- Moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China;Institute of Acupuncture andMoxibustion,China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《医疗卫生装备》
CAS
2019年第5期43-47,53,共6页
Chinese Medical Equipment Journal
基金
新奥集团资助项目(201803)
关键词
经皮二氧化碳释放率
经皮二氧化碳分压
能量代谢
激光多普勒仪
二氧化碳分压单元
transcutaneous CO2 emissing rate
transcutaneous carbon dioxide partial pressure
energy metabolism
laser Doppler instrument
carbon dioxide partial pressure unit
