摘要
目的探讨目标降幅欠矫对角膜塑形镜控制近视效果的影响,以及目标降幅同角膜中央上皮受损的关系。方法回顾性研究2016年1月—2017年2月门诊验配的22例目标降幅欠矫的角膜塑形镜配戴者(37只眼)资料,并随机抽取25例同时段全矫配戴者(47只眼)作为对照。分析其戴镜前后眼轴变化情况、戴镜6个月内角膜中央上皮受损情况。结果目标降幅欠矫组的眼轴年平均增长值为(0.13±0.15)mm,目标降幅足矫组的眼轴年平均增长值为(0.14±0.16)mm,两组比较差异无统计学意义(P>0.05)。多重线性回归分析显示,眼轴增长与目标降幅欠矫量无相关关系(P>0.05),与年龄呈负相关(P<0.01)。配戴角膜塑形镜后,7～10岁儿童的眼轴年平均增长值为(0.25±0.16)mm,11～15岁儿童的眼轴年平均增长值为(0.10±0.14)mm,差异有统计学意义(P<0.01)。目标降幅–4.25～–5.00 D组角膜中央上皮点状染色率为27.08%,目标降幅–3.00～–4.00 D组角膜中央上皮点状染色率为16.67%,差异无统计学意义(P>0.05)。结论角膜塑形镜控制近视增长的效果不受近视目标降幅欠矫的影响,与目标降幅欠矫量不相关,同年龄负相关,近视度数较高者依然可以通过欠矫的角膜塑形镜达到控制近视增长的效果。暂未发现目标降幅同角膜中央染色存在相关关系。
Objective To investigate the influence of undercorrected orthokeratology on myopia control,and the correlation between target and central corneal epithelial damage.Methods A retrospective study was conducted on22 undercorrected orthokeratology lens wearers(37 eyes)from January 2016 to February 2017,and 25 full corrected wearers(47 eyes)during the concurrent period were randomly selected as the control group.The changes of axial length before and after orthokeratology lens wearing and the within-6-month central corneal epithelial damage after orthokeratology lens wearing were analyzed.Results The average annual increase of axial length was(0.13±0.15)mm in the undercorrected group,and(0.14±0.16)mm in the full corrected group,the difference was not statistically significant(P>0.05).Multiple linear regression analysis showed that there was no correlation between the axial growth and the undercorrection of the target(P>0.05),but a negative correlation between the axial growth and the age(P<0.01).After using orthokeratology,the average annual growth of the axial length in children aged 7-10 years was(0.25±0.16)mm,and(0.10±0.14)mm in children aged 11-15 years,the difference was statistically significant(P<0.01).The incidence of central corneal epithelial punctate staining in the(–4.25)-(–5.00)D target group was 27.08%,and that in the(–3.00)-(–4.00)D target group was 16.67%,the difference was not statistically significant(P>0.05).Conclusions The effect of orthokeratology on myopia growth is not affected by the undercorrected target,not related to the undercorrection of target,but negatively correlated with the age.Undercorrected orthokeratology can still be used for myopia control in high myopia patients.No correlation is found between the target and central corneal staining.
作者
董光静
刘陇黔
DONG Guangjing;LIU Longqian(Department of Ophthalmology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)
出处
《华西医学》
CAS
2019年第4期405-409,共5页
West China Medical Journal
