摘要
目的观察盆腔自主神经功能保留对宫颈癌患者早期性生活质量的影响。方法回顾性分析2015年4月至2017年8月十堰市妇幼保健院96例宫颈癌患者的临床资料,根据手术方式不同分为观察组和对照组,各48例。观察组采取保留盆腔自主神经根治性子宫切除(nerve sparing radical hysterectomy,NSRH),对照组采取常规根治性宫颈癌术。比较两组手术时间、术中出血量、排气时间、排便时间、住院时间、并发症总发生率、术后3个月的膀胱最大容量、残余尿量<50 mL时间、残余尿量<100 mL时间及术前与术后3个月的性生活质量[采用女性性功能量表(Female Sexual Function Index,FSFI)评估]。结果两组手术时间比较,差异无统计学意义(P>0.05);观察组术中出血量、排气时间、排便时间及住院时间均短于对照组(P<0.05)。观察组并发症总发生率(4.16%)低于对照组(16.65%),差异有统计学意义(P<0.05)。观察组术后3个月膀胱最大容量高于对照组,残余尿量<50 mL时间、残余尿量<100 mL时间短于对照组(P<0.05)。两组术前FSFI评分比较,差异无统计学意义(P>0.05);术后3个月两组FSFI评分均较治疗前降低(P<0.05)。观察组术后3个月FSFI评分高于对照组[(18.85±3.11)分vs (16.95±3.44)分](P<0.05)。结论 NSRH治疗宫颈癌患者在达到根治目的的同时还能尽可能保留盆腔自主神经,减轻对直肠、膀胱的影响,减少术后并发症,促进术后早期性生活质量的提高。
Objective To investigate the effect of pelvic autonomic nerve function retention on early sexual life quality in patients with cervical cancer. Methods A total of 96 cases of cervical cancer in Shiyan Maternal and Child Health Hospital from April 2015 to August 2017 were selected for prospective study and divided into observation group and control group according to the random number table method, with 48 cases in each group. The observation group was treated with nerve sparing radical hysterectomy(NSRH), and the control group received routine radical cervical cancer surgery. The operation time, intraoperative blood loss, excretion time, defecation time, hospitalization time, the total incidence of complications, the maximum bladder capacity, time of residual urine output < 50 mL, time of residual urine output < 100 mL at 3 months after operation and the sexual quality of life before operation and 3 months after operation [assessed using the female sexual function index(FSFI)] were compared between two groups. Results There was no significant difference in operative time between the two groups(P>0.05). The intraoperative blood loss, excretion time, defecation time, hospitalization time in the observation group were significantly shorter than those in the control group(P<0.05). The overall incidence of complications in the observation group was 4.16 %, which was significantly lower than 16.65 % in the control group(P<0.05). The maximal bladder capacity of the observation group was significantly higher than that of the control group at 3 months after operation. The time of residual urine output <50 mL, time of residual urine output <100 mL at 3 months after operation in observation group were significantly shorter than those in the control group(P<0.05). The FSFI scores of the two groups before operation were not statistically significant(P>0.05). The FSFI scores of the two groups at 3 months after operation were significantly lower than those before operation(P<0.05). The FSFI score of the observation group at 3 m
作者
朱定军
叶梅
ZHU Ding-jun;YE Mei(Department of Obstetrics and Gynecology, Zhuhai Peoples Hospital,Zhuhai Guangdong 519000, P. R. China)
出处
《中国计划生育和妇产科》
2019年第4期82-85,共4页
Chinese Journal of Family Planning & Gynecotokology
关键词
宫颈癌
盆腔自主神经
膀胱
性生活质量
cervical cancer
pelvic autonomic nerve
bladder
quality of sexual life