摘要
目的 探究前循环新发脑梗死(ACI)患者头晕症状与颈内动脉(ICA)系统血管病变的关系。方法纳入前循环新发脑梗死患者234例,均接受全脑血管造影(DSA)检查,排除椎基底动脉(VBA)系统血管异常,根据发病前24 h内是否出现头晕症状,分为头晕组与非头晕组。收集患者人口学特征、一般临床资料、影像学资料,进行两组间脑血管危险因素(VRFs)、责任梗死部位、颈内动脉(ICA)系统、侧支循环建立的差异分析。结果 单因素分析高血压、总胆固醇、低密度脂蛋白胆固醇(LDL-C)、VRFs≥3、一侧ICA狭窄合并迂曲、ICA中度迂曲差异有统计学意义(P <0. 05),多因素回归分析显示LDL-C、一侧ICA狭窄合并迂曲为ACI患者伴随头晕症状的脑血管独立危险因素。结论 合并低密度脂蛋白胆固醇越高的ACI患者头晕发生比例增加。一侧颈内动脉存在狭窄合并迂曲,为ACI出现头晕症状的独立危险因素,值得临床工作者重视。
Objective To explore the risk factors of dizziness in patients with anterior circulation infarction(ACI)and its relationship with the morphological changes of internal carotid artery(ICA)system.Methods 234 patients with new cerebral infarction in anterior circulation were enrolled in this study.All patients underwent DSA to exclude abnormal blood vessels in vertebrobasilar artery(VBA)system.the patients were divided into dizziness group and non-dizziness group based on whether dizziness occurred within 24 hours before onset.The demographic characteristics,general clinical data and imaging data of the patients were collected.The morphological changes of arteries in ICA system,the patterns of collateral circulation and vascular risk factors(VRFs)between the two groups were analyzed.Results Univariate analysis showed that hypertension,total cholesterol,low density lipoprotein cholesterol(LDL-C),VRFs≥3,one side ICA stenosis with tortuosity,ICA moderate tortuosity had significant difference(P<0.05).Multivariate regression analysis showed that LDL-C and one side ICA stenosis with tortuosity were independent risk factors for dizziness in ACI patients.Conclusion The higher the LDL-cholesterol,the higher the incidence of dizziness in ACI patients.The presence of stenosis and tortuosity in one internal carotid artery is an independent risk factor for dizziness symptoms in ACI patients,which deserves the attention of clinical workers.
作者
易兰
倪健强
杨怡尧
徐敏
方琪
董万利
YI Lan;NI Jianqiang;YANG Yiyao(Department of Neurology,the First Affiliated Hospital of Soochow University,Suzhou 215006,China)
出处
《中风与神经疾病杂志》
CAS
2019年第4期307-311,共5页
Journal of Apoplexy and Nervous Diseases
基金
江苏省六大人才高峰计划(WSW-016)
江苏省青年医学人才项目(QNRC2016729)
苏州市民生科技计划(SYS201607)
关键词
颈内动脉系统新发脑梗死
头晕
血管迂曲
侧支循环
New cerebral infarction of internal carotid artery system
Dizziness
Vascular tortuosity
Collateral circulation
