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转化生长因子β1在子宫内膜异位症和子宫内膜癌中的表达 被引量:4

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摘要 转化生长因子β1(transforming growth factor β1,TGF-β1)对细胞的生长、分化具有重要调节作用,是作用于上皮细胞的重要生长因子之一,可促使细胞增殖和转化,诱导新生血管形成,在肿瘤的发生、发展中起双向调节作用。研究发现,TGF-β1通过多种途径在子宫内膜异位症(endometriosis,EMs)发生发展过程中发挥重要作用。而且,TGF-β1在子宫内膜癌(endometrial carcinoma)形成早期起抑制作用,在随后发展过程中起促进作用。本文就TGF-β1在上述2种疾病中的表达做一综述。
作者 端娅 陈颖
出处 《云南医药》 CAS 2019年第2期164-166,共3页 Medicine and Pharmacy of Yunnan
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