摘要
目的分析铜绿假单胞菌医院感染的现状及对常用药物的耐药性。方法搜集我院自2014年6月～2017年12月分离鉴别出的80株铜绿假单胞菌,菌株均来源于不同患者的标本,分析该病原菌的标本来源、科室来源和对常用药物的耐药性。结果铜绿假单胞菌的标本来源以痰液为主,比例为56.25%(45株),其次为脓液15.00%;科室来源以呼吸内科为主,比例为25.00%(20株),其次为重症监护室22.50%;在耐药性上,对氨苄西林、头孢噻肟、头孢西丁、头孢唑啉、头孢曲松的耐药性较高,均高于90%,而对阿卡米星、亚胺培南的耐药性较低;多重耐药菌株和泛耐药菌株的科室来源以重症监护室为主,比例为72.22%(13/18株),其次为呼吸内科11.76%。结论铜绿假单胞菌多来源于呼吸内科,多重耐药菌株和泛耐药菌株多来源于重症监护室,其耐药性较高,临床需加强控制和监测。
Objective To analyze the current situation of Pseudomonas aeruginosa infection and its resistance to drugs.Methods 80 strains of Pseudomonas aeruginosa identified from different patients'specimens in our hospital from September 2014 to September 2018 were collected.The source of specimens, department sources and drug resistance were analyzed.Results The main source of Pseudomonas aeruginosa was sputum(56.25%,45 strains), followed by pus(15.00%).The main department sources was respiratory medicine(25.00%, 20 strains) and ICU (22.50%).The drug resistance to ampicillin,cefotaxime,cefoxitin,cefazolin and ceftriaxone was high and more than 90%,while the resistance to Acamicin and Imipenem was lower.The major source of multi-drug resistant and pan-drug resistant strains was ICU(72.22%), followed by (11.76%).Conclusion Pseudomonas aeruginosa mostly comes from respiratory medicine, and multidrug-resistant and pan-drug-resistant strains mostly come from ICU, and drug resistance is high. Monitoring should be strengthened in the clinic.
作者
马继明
宋成福
MA Ji-ming;SONG Cheng-fu(Four Departments of Geriatrics of Yangpu Hospital Affiliated to Tongji University, Shanghai 200093 China)
出处
《现代诊断与治疗》
CAS
2019年第3期342-344,共3页
Modern Diagnosis and Treatment
关键词
铜绿假单胞菌
现状
耐药性
标本
Pseudomonas Aeruginosa
Current Situation
Drug Resistance
Specimens
