摘要
男性不育症发病率逐年增加,而临床上对于男性生育能力的评估仍然主要依赖精液常规检测,已不能满足现今临床的要求,一些新的检测指标开始被发现并发挥着重要的作用。精子顶体酶活性作为评价男性生育能力指标,已在临床应用多年,一直是男性不育的研究热点。该文就精子顶体酶活性的功能作用、影响因素、药物治疗及其与辅助生殖的研究进展作一综述,为男性不育的诊断与治疗提供新思路。
The morbidity of male infertility increases progressively year by year,but clinically,the evaluation of male fertility still mainly relies on routine semen analysis.It is not enough to meet the requirement in current clinic practice.Some new indexes have been discovered and play important roles in this field.As one of the indicators for male fertility,acrosin activity has become a research hotspot for many years.In this paper,we review the function of acrosin activity,influencing factors,drug treatments and the research advances in assisted reproduction to provide a new idea for the diagnosis and treatment of male infertility.
作者
李远发
梁季鸿
LI Yuan-fa;LIANG Ji-hong(Department of Andrology and Sexual Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China)
出处
《中国临床新医学》
2019年第4期463-467,共5页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
