摘要
目的探讨绝经后子宫内膜增厚患者子宫内膜恶变的风险。方法回顾性分析自2017年1月—2018年8月首都医科大学附属北京世纪坛医院妇科病房收治的523例绝经后超声提示子宫内膜增厚患者,根据其宫腔镜检查病理结果,分析其子宫内膜恶变的风险。结果 523例绝经后子宫内膜增厚患者病理诊断结果为正常子宫内膜24例(4.6%)、子宫内膜息肉268例(51.2%)、子宫内膜炎44例(8. 4%)、粘膜下子宫肌瘤16例(3.1%)、宫腔粘连53例(10.1%)、良性子宫内膜增生89例(17.0%)、非典型子宫内膜增生13(2.5%)、子宫内膜癌16例(3.1%)。BMI≥25、有阴道出血或排液症状、内膜厚度≥10mm是子宫内膜恶性病变的独立危险因素(P<0. 05)。结论重视子宫内膜癌的高危因素,进行必要的宫腔镜检查及早发现子宫内膜恶性病变同时减少无子宫内膜病变患者的有创操作,从而减少患者的痛苦及医疗资源的浪费。
Objective To investigate the clinical features and pathological types of postmenopausal endometrial thickening patients and to analyze the risk of endometrial malignancy. Methods 523 cases of postmenopausal women with endometrial thickening were recruited from January 2017 to August 2018. According to the pathological results of hysteroscopy, the risk of endometrial malignancy was analyzed. Results The pathological diagnosis of 523 postmenopausal endometrial thickening patients included 24 cases of normal endometrium(4.6%), 268 cases of endometrial polyps(51.2%), 44 cases of endometritis(8.4%), 16 cases of submucous myomas(3.1%), 53 cases of intrauterine adhesions(10.1%), 89 cases of benign endometrial hyperplasia(17.0%), 13 cases of atypical endometrial hyperplasia(2.5 %) and 16 cases of endometrial carcinoma(3.1 %).BMI≥25, vaginal bleeding or drainage symptoms, and endometrial thickness≥10 mm were independent risk factors for endometrial malignancy(P<0.05). Conclusion Attention should be paid to the high risk factors of endometrial cancer, and it’s necessary to perform hysteroscopy to detect endometrial malignant lesions and to reduce invasive procedures for patients without endometrial lesions, which could reduce the suffering of patients and wasting medical resources.
作者
尹聪
白文佩
YIN Cong;BAI Wenpei(Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Beijing 100038,China)
出处
《中国生育健康杂志》
2019年第3期215-217,共3页
Chinese Journal of Reproductive Health
关键词
绝经期
子宫内膜增厚
子宫内膜恶变
Menopausal period
Thickening of endometrium
Endometrial malignancy
