摘要
目的评估维持性血液透析(maintenance hemodialysis, MHD)患者心理功能及认知功能情况,分析其相关影响因素。方法选择2017年5月1日～2018年5月1日中国康复研究中心北京博爱医院规律血液透析超过3个月的MHD患者113例,以焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS)评估MHD患者心理功能状况;简易精神状态评价量表(mini-mental state examination,MMSE)评估MHD患者认知功能状况。结果①心理功能:MHD患者焦虑患病率为8.6%,其中轻度、中重度的焦虑患病率分别为5.2%、3.4%;MHD患者抑郁患病率为69%,其中轻度、中度、重度的抑郁患病率分别为29.3%、21.6%、18.1%。②认知功能:33.6%的MHD患者存在认知功能障碍。脑血管疾病是MHD患者认知功能障碍的独立危险因素,合并脑血管病的MHD患者认知功能障碍的风险显著增加(OR=3.092,95%CI:1.192～8.025,P=0.020)。结论 MHD患者心理功能障碍高发,而且存在不同程度的认知功能障碍,脑血管病是认知功能障碍的独立危险因素。
Objective To evaluate the psychological and cognitive functions and their influential factors in maintenance hemodialysis(MHD)patients.Methods A total of 113 MHD patients with regular hemodialysis for more than three months in Beijing Bo’ai Hospital of China Rehabilitation Research Center in the period from May 1,2017 to May 1,2018 were enrolled in this study.Psychological function was assessed by Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS),and cognitive function was assessed by Simple Mental State Assessment Scale(MMSE).Results For psychological function in MHD patients,the prevalence rate of anxiety was 8.6%(mild anxiety 5.2%and severe anxiety 3.4%);the prevalence of depression was 69%(mild depression 29.3%,moderate depression 21.6%and severe depression 18.1%).For cognitive function in MHD patients,the prevalence of cognitive dysfunction was 33.6%;cerebrovascular disease was an independent risk factor for cognitive impairment,and the risk of cognitive impairment increased significantly in MHD patients with cerebrovascular disease(OR=3.092,95%CI:1.192~8.025,P=0.020).Conclusion MHD patients have a higher prevalence rate of psychological disorders and cognitive dysfunction at various degrees.Cerebrovascular disease is an independent risk factor for cognitive dysfunction.
作者
张兰
孙超
程艳娇
马迎春
ZHANG Lan;SUN Chao;CHENG Yan-jiao;MA Ying-chun(Department of Nephrology,Beijing Bo’ai Hospital,China Rehabilitation Research Center,School of Rehabilitation Medicine,Capital Medical University,Beijing 100068,China)
出处
《中国血液净化》
CSCD
2019年第2期107-109,共3页
Chinese Journal of Blood Purification
基金
中国康复研究中心课题2017ZX-05
关键词
血液透析
心理功能
认知功能
Hemodialysis
Psychological function
Cognitive function
