摘要
肝脏储备功能的评估对扩大肝切除术和门静脉栓塞患者至关重要,但尚无任何一种检查方法能够全面准确地评估肝脏储备功能。目前应用于肝脏储备功能评估的各种方法主要包括生物化学指标、临床评分系统(如 Child-Pugh 和 MELD 评分等)、动态定量检测肝脏清除功能(如吲哚靛青绿清除试验)、核素显像(如^(99m)锝-半乳糖基人血白蛋白显像和^(99m)锝-甲溴苯宁肝胆特异核素显像等)、CT 灌注成像、MRI(如 Gd-EOB-DTPA 增强 MRI)等。该文将综述各种方法的基本原理,并比较各种检查方法的优缺点。
The evaluation of hepatic functional reserve is of great importance for patients undergoing extended hepatectomy and portal vein embolization. However, there has been no exact method to comprehensively and accurately evaluate the hepatic functional reserve at present. Various methods were currently used to assess the hepatic functional reserve ,including biochemical index, clinical scoring system (such as Child-Pugh and MELD), dynamic quantitative detection of hepatic clearance functio(n such as indocyanine green clearance test), radionuclide imaging( such as 99mTc-galactosyl-human serum albumin imaging and 99mTc-mebrofenin hepatobiliary specific nuclide imaging), CT perfusion imaging, magnetic resonance imaging examination( such as Gd-EOB-DTPA enhanced MRI), etc. The principles of these methods were summarized and their advantages and disadvantages were compared in this article.
作者
梁伟强
王猛
Liang Weiqiang;Wang Meng(Department of Radiology, Xinhui Hospital of TCM, Jiangmen 529100, China)
出处
《新医学》
2019年第4期229-233,共5页
Journal of New Medicine
关键词
肝脏
储备功能评估
肝功能
核素
磁共振成像
Liver
Evaluation of hepatic functional reserve
Liver function
Radionuclide
Magnetic resonance imaging
