摘要
【目的】评价针刺联合康复疗法治疗中风后吞咽障碍的临床疗效及安全性。【方法】检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普期刊数据库(VIP)、万方数据库中近10年来发表于期刊的针灸联合康复疗法对比单纯康复疗法和/或常规西药干预(对照组)治疗中风后吞咽障碍的临床随机对照试验文献,对纳入的文献质量进行评价后,采用RevMan 5.3软件进行Meta分析。【结果】最终纳入文献16篇,总病例数为1 780例。Meta分析结果显示,针刺联合康复疗法治疗中风后吞咽障碍的总有效率优于对照组(RR=1.22,95%CI[1.16,1.28],Z=7.80,P<0. 01);在改善洼田饮水试验评分(MD=-0.66,95%CI[-0.78,-0.53],Z=10.62)及改善吞咽障碍临床评价量表评分(MD=2.01,95%CI[1.78,2.24],Z=17.30)方面均优于对照组(P<0. 01)。【结论】针刺联合康复疗法治疗中风后吞咽障碍具有较好的疗效;但因所纳入分析的文献质量不高,结论有待更高质量的临床试验验证。
Objective To systematically evaluate the effectiveness and safety of acupuncture combined with rehabilitation therapy for the treatment of dysphagia after stroke.Methods Randomized clinical trials(RCTs)of acupuncture combined with rehabilitation therapy versus rehabilitation alone or/and conventional western medicine(control group)for the treatment of dysphagia after stroke issued in the periodicals enrolled in the databases of CBM,CNKI,VIP and Wanfang were analyzed.The literature quality of the qualified RCTs was evaluated,and then RevMan 5.3 software was used for the Meta analysis.Results Sixteen RCTs involving a total of 1780 cases were included the analysis.The results of Meta-analysis showed that acupuncture combined with rehabilitation therapy had higher total effective rate(RR=1.22,95%CI[1.16,1.28],Z=7.80,P<0.01),and had stronger effect on improving the scores of Kubota Water Swallowing Test(MD=-0.66,95%CI[-0.78,-0.53],Z=10.62)and dysphagia scale(MD=2.01,95%CI[1.78,2.24],Z=17.30)than the control group(P<0.01).Conclusion Acupuncture combined with rehabilitation therapy exerts certain effects for the treatment of dysphagia after stroke;for the quality of the included studies is low,the conclusion still need high-quality RCTs to verify.
作者
汤小荣
王琳
黄培冬
兰俊超
许能贵
TANG Xiao-Rong;WANG Lin;HUANG Pei-Dong;LAN Jun-Chao;XU Neng-Gui(Guangzhou University of Chinese Medicine,Guangzhou 510006 Guangdong,China;Yunnan University of Traditional Chin ese Medicine,Kunming 650500 Yunnan,China)
出处
《广州中医药大学学报》
CAS
2019年第4期514-520,共7页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(编号:81230088)
广东省教育厅特色创新项目(编号:2016KQNCX027)
关键词
中风
吞咽障碍
针刺疗法
康复疗法
META分析
stroke
dysphagia
acupuncture therapy
rehabilitation therapy
Meta-analysis
