摘要
目的分析老年原发性高血压患者血压变异性与靶器官损害的关系。方法选取2015年1月至2017年1月老年原发性高血压患者50例作为研究对象,视作老年组,另外在同期选取60岁以下的原发性高血压患者50例作为非老年组,两组均进行动态血压监测,进行血压变异系数计算,比较两组肾功能、心脑血管合并症情况。结果老年组24 h平均收缩压、日间平均收缩压、夜间平均收缩压均明显高于非老年组,舒张压均明显低于非老年组,差异有统计学意义(P <0. 05);两组有合并症的患者24 h血压变异、日间血压变异、夜间血压变异均高于无合并症的患者,老年组不同时间收缩压变异水平均明显高于非老年组,24 h以及日间舒张压变异均低于非老年组,老年组夜间血压变异水平明显高于非老年组,差异有统计学意义(P <0. 05);老年组24 h尿微量白蛋白水平明显高于非老年组,差异有统计学意义(P <0. 05),老年组与非老年组血清尿素氮、血肌酐水平差异不明显,差异未见统计学意义(P> 0. 05),老年组左室质量指数明显高于非老年组,差异有统计学意义(P <0. 05)。结论老年原发性高血压血压变异性与靶器官损害存在紧密联系,血压变异会增加靶器官损害发生率,临床应该加强重视。
Objective To analyze the relationship between blood pressure variability and targetorgan damage in elderly patients with essential hypertension.Methods From January 2015 to January2015 in our hospital,50 elderly patients with essential hypertension were selected as the researchobjects,as the elderly group,at the same period,50 patients with essential hypertension under the age of60 cases were selected as the non elderly group.Both groups had ambulatory blood pressure monitoring,the blood pressure variation coefficient was calculated,the renal function and cardiovascularcomplications were compared.Results The average systolic blood pressure,daily average systolic bloodpressure and average systolic blood pressure were significantly higher than those in the non-elderly group,and the diastolic pressure was significantly lower than that in the non-elderly group(P<0.05).The 24 hblood pressure variation,daytime blood pressure variation,nocturnal blood pressure variation were higherof the patients with complications in the two groups than the patients without complications,the differenttime systolic blood pressure variation levels in the elderly group were significantly higher than that of non-elderly group.The 24 h blood pressure and diastolic blood pressure variation in the day were lower thanthat in the non-elderly group,the nocturnal blood pressure variation level was obviously higher than thatof non-elderly group(P<0.05).The 24 h urine trace albumin levels were significantly higher in theelderly group than those of non elderly group(P<0.05).The serum urea nitrogen,serum creatininelevel difference was not obvious(P>0.05).The left ventricular mass index was significantly higher thanthat of the elderly group(P<0.05).Conclusions There is close relationship between the bloodpressure variability of senile primary hypertension and target organ damage,and the blood pressurevariation can increase the incidence of target organ damage,and the clinicians should pay more attentionto it.
作者
窦安明
孙玉丽
Dou Anming;Sun Yuli(Department of Cardiology,Haining Kanghua Hospital,HaiNing 314400,China)
出处
《临床医学》
CAS
2018年第12期9-12,共4页
Clinical Medicine
关键词
老年
原发性高血压
血压变异性
靶器官损害
Old age
Essential hypertension
Blood pressure variability
Target organ damage
