摘要
目的对比固尔苏、珂立苏治疗早产儿呼吸窘迫综合征(RDS)的临床疗效。方法选取我院新生儿科收治的RDS早产儿80例,随机分为两组。对照组(38例)予以珂立苏治疗,观察组(42例)予以固尔苏治疗,比较两组患者的治疗效果。结果两组患儿治疗前后的pH、 PaCO2、 PaO2水平比较均无统计学差异(P>0.05)。治疗后4 h,观察组的氧合指数、平均气道压均明显低于对照组(P <0.05);治疗后24 h、 48 h,两组的氧合指数、平均气道压比较均无统计学差异(P>0.05)。两组患儿的住院时间、机械通气时间比较均无统计学差异(P>0.05)。结论固尔苏、珂立苏治疗早产儿RDS均有显著效果,且在改善患儿血气分析结果、氧合指数方面的效果相当。与珂立苏相比,固尔苏起效更为迅速,临床可优先考虑。
Objective To compare the clinical efficacy of curosurf and calsurf in the treatment of respiratory distress syndrome(RDS in premature infants. Methods 80 cases of RDS premature infants admitted to our department of neonatology were selected and randomly divided into two groups. The control group(38 cases) was treated with calsurf, and the observation group(42 cases) was treated with curosurf. The treatment effects of the two groups were compared. Results No statistical difference was found in the pH, PaCO2 and PaO2 levels before and after treatment between the two groups(P>0.05). 4 h after treatment, the oxygenation index and mean airway pressure of the observation group were significant ly lower than those of the control group(P<0.05). 24 h and 48 h after treatment, no statistical difference was found in the oxygenation index and mean airway pressure between the two groups(P>0.05). No statistical difference was found in the hospitalization time and mechanical ventilation time between the two groups(P>0.05). Conclusions Both curosurf and calsurf have significant effects in the treatment of RDS premature infants, and have similar effects in the improvement of blood gas analysis results and oxygenation index. Compared with calsurf, curosurf is more effective and can be given clinical priority.
作者
朱超梅
ZHU Chaomei(Department of Neonatology,Dengfeng People's Hospital,Dengfeng 452470,China)
出处
《临床医学工程》
2019年第3期341-342,共2页
Clinical Medicine & Engineering
关键词
早产儿
呼吸窘迫综合征
固尔苏
珂立苏
血气分析结果
氧合指数
Premature infants
Respiratory distress syndrome
Curosurf
Calsurf
Blood gas analysis results
Oxygenation index
