摘要
随着城市化的进展空气污染逐渐加重,尤其颗粒物(PM)2.5对人体的危害极大而受到重视。近年来,PM2.5已成为加重哮喘的重要原因之一,研究发现可以单独导致哮喘。对哮喘的影响已涉及到基因、表观遗传及细胞自噬水平。除一般防护措施外,尚无西药应用于临床,中医防护则成为一大优势。本文从PM2.5的来源和性质、PM25对人体健康的影响、致病机制及防护进行了综述。
Air pollution has gradually increased with the progress of urbanization.In particular,particulate matter(PM)2.5 is extremely harmful to the human body and is valued.In recent years,PM2.5 has become one of the important reasons for aggravating asthma.And relevant study has found that asthma can be caused alone by PM2.5.This article summarizes the source and nature of PM2.5,the impact of PM2.5 on human health,pathogenesis and protection,and its impact on asthma has involved the level of genes,epigenetics and autophagy,in addition to general protective measures.There is no western medicine used in clinical practice,and Chinese medicine protection has become a major advantage.
作者
王瑞茵
林江涛
Wang Ruiyin;Lin Jingtao(Graduate School of Beijing University of Chinese Medicine,Beijing 100029,China;Department of Respiratory and Critical Care Medicine,China-Japan Friendship Hospital,Beijing 100029,China)
出处
《国际呼吸杂志》
2019年第5期362-366,共5页
International Journal of Respiration
基金
首都卫生发展科研专项重点攻关项目(2016-1-4061)
北京市科委首都临床特色应用研究重点项目(2015-BKJ-001).
关键词
颗粒物2.5
哮喘
机制
中医
Particulate matter 2.5
Asthma,bronchial
Mechanism
Chinese medicine
