摘要
高钙血症是一种钙代谢异常,可由多种疾病引起,其中结节病引起高钙血症比较少见。结节病是一种病因不明的系统性肉芽肿疾病,临床症状缺乏特异性,容易引起误诊。本文报告1例以高钙血症及纵隔淋巴结肿大为表现的结节病患者,首诊考虑肿瘤,经淋巴结穿刺活检后确诊为结节病。在接受泼尼松治疗后,患者症状明显缓解,血钙水平恢复正常,纵隔淋巴结较前缩小。该病例提示临床医生需提高对结节病的认识,以便发现并做出诊断。
Hypercalcemia is an abnormal calcium metabolism, which can be caused by many diseases. Hypercalcemia caused by sarcoidosis is unusual. Sarcoidosis is a systemic granulomatous disease, it is lack of specificity in initial manifestations and easy to be misdiagnosed. In this paper, we report a patient with hypercalcemia and mediastinal lymphadenectasis, which the first diagnosis was misdiagnosed as tumour. Finally, sarcoidosis was diagnosed by mediastinal lymph node biopsy, and the patient was subsequently treated with glucocorticoid. Prednisone treatment improved symptoms of sarcoidosis, normalised serum calcium and mediastinal lymph nodes were diminished. This case suggests that clinicians need to raise awareness of sarcoidosis to identify and diagnose it correctly.
作者
李剑
高清歌
徐立
祝超瑜
肖元元
喻晶
蒋伏松
魏丽
Li Jian;Gao Qingge;Xu Li;Zhu Chaoyu;Xiao Yuanyuan;Yu Jing;Jiang Fusong;Wei Li(Department of Endocrinology and Metabolism, Shanghai Sixth People′s Hospital East Branch Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201306, China;Department of Cardiology, Shanghai Sixth People′s Hospital East Branch Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201306, China)
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2019年第2期157-160,共4页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金(81500615).
关键词
高钙血症
纵隔淋巴结肿大
结节病
Hypercalcemic
Mediastinal lymphadenectasis
Sarcoidosis
