摘要
帕金森病是一种缓慢进展的神经系统退行性疾病,严重影响中老年人的日常生活,给家庭和社会带来了沉重负担。帕金森病的病理生理机制复杂,目前其病因尚不明确。研究表明,帕金森病的发生发展是复杂的遗传和环境因素相互作用的结果。该研究从多角度回顾了与帕金森病相关的危险因素,希望为帕金森病的早期干预和预防提供新的思路。
Parkinson's disease (PD) is a slowly progressive neurodegenerative disease that seriously affects the daily life of middle-aged and elderly people, and places a heavy burden on families and society. The pathophysiological mechanism of PD is complex, and its etiology is still unclear. Studies have shown that the occurrence and development of PD resulted from the interactions between complex genetic and environmental factors. This article reviews the risk factors associated with PD from multiple perspectives, might providing new insights into early intervention and prevention of Parkinson's disease.
作者
宋亚南
郁金泰
谭兰
Song Yanan;Yu Jintai;Tan Lan(Department of Neurology,Qingdao Municipal Hospital,Qingdao University,Qingdao 266071,China;Clinical Research Center,Qingdao Municipal Hospital,Qingdao University,Qingdao 266071,China;College of Medicine and Pharmaceutics,Ocean University of China,Qingdao 266003,China)
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2019年第2期188-192,共5页
Chinese Journal of Behavioral Medicine and Brain Science
基金
国家自然科学基金项目(81571245).
关键词
帕金森病
危险因素
预防
Parkinson's disease
Risk factors
Prevention
