摘要
目的分析瞬态诱发性耳声发射(TEOAE)技术联合自动听性脑干反应(AABR)检查在高危新生儿听力筛查中的临床意义。方法纳入新生儿重症监护病房(NICU)自2016年7月～2018年7月收治的高危新生儿312例(624耳),于出生后3～20 d行听力障碍初筛,其中采取TEOAE技术检查法筛查出双耳均通过者159例(318耳)设为通过组,均未通过者153例(306耳)设为未通过组。于出生后42 d、90 d行第1次复筛、第2次复筛,比较TEOAE技术检查法、AABR检查法分别与联合法检测的通过率,比较三种筛查法在通过组与未通过组初筛、复筛中的通过率。结果 TEOAE技术检查法初筛、第1次复筛的通过率分别为50.96%、88.14%,均明显高于联合法的43.43%、83.17%(P<0.05)。AABR检查法初筛、第2次复筛的通过率分别为77.72%、94.87%,均明显高于联合法的43.43%、88.30%(P<0.05)。通过组初筛、第1次复筛、第2次复筛采取联合筛查法检测的通过率分别为85.22%、88.05%、94.97%,均明显高于未通过组的0、78.10%、81.37%(P<0.05)。结论 TEOAE技术联合AABR检查能够对单一筛查法进行有效补充,有助于降低高危新生儿听力筛查的假阳性率及漏诊率。
Objective To analyze the clinical significance of transient evoked otoacoustic emissions (TEOAE) combined with automatic auditory brainstem response(AABR) in high-risk neonatal hearing screening. Methods A total of 312 high-risk neonates(624 ears) were enrolled in the neonatal intensive care unit(NICU) from July 2016 to July 2018. Hearing impairment screening was performed at 3-20 days after birth. 159 cases(318 ears) with both ears successfully passing by the TEOAE technical inspection method were set as the passing group. And 153 cases (306 ears) not passed were set as the unpassed group. The first re-screening and the second re-screening were performed at 42 d and 90 d after birth. The passing rate of TEOAE technical inspection method, AABR inspection method to combined method detection was compared. The passing rates of three screening methods were compared in primary screening and rescreening in the passing group and the non-passing group. Results The pass rates of the first screening and the first screening of TEOAE technical examination were 50.96% and 88.14%, respectively, which were significantly higher than 43.43% and 83.17% of combined methods(P<0.05). The pass rates of the first screening and the second screening of AABR were 77.72% and 94.87%, respectively, which were significantly higher than 43.43% and 88.30% of combined methods(P<0.05). The pass rates of the combined screening in the first screening and the second screening of the passing group were 85.22%, 88.05%, and 94.97%, respectively, which were significantly higher than 0, 78.10%, and 81.37% of the unpassed group(P<0.05). Conclusion TEOAE combined with AABR can effectively supplement the single screening method, helping to reduce the false positive rate and missed diagnosis rate of hearing screening in high-risk newborns.
作者
勾晶
GOU Jing(Jiamusi Maternal and Child Health Hospital in Heilongjiang Province, Jiamusi 154002, China)
出处
《中国现代医生》
2019年第6期18-21,共4页
China Modern Doctor
关键词
瞬态诱发性耳声发射技术
自动听性脑干反应
高危新生儿
听力筛查
Transient evoked otoacoustic emission technique
Automatic auditory brainstem response
High-risk newborns
Hearing screening
