期刊文献+

腮腺原发性淋巴瘤的CT征象与Ki-67指数及预后关系 被引量:3

An investigation on the features of parotid primary lymphoma in CT images and their relationship with Ki-67 index and prognosis
下载PDF
导出
摘要 目的观察腮腺原发性淋巴瘤(PPL)的CT表现、分析其CT征象与Ki-67指数及预后关系。方法回顾性分析经病理证实的37例腮腺原发性淋巴瘤,观察其CT表现,利用R×C列表卡方检验观察CT征象(大小、部位、形态、边界及强化程度)与Ki-67指数关系,用Kaplan-Meier法计算15例患者5年生存率,用Logrank法计算性别、年龄、Ki-67指数及CT征象与生存情况的关系。结果腮腺原发性淋巴瘤以MALTL及FL最多见,CT多表现为多发或弥漫结节型,中度均匀强化,边界清楚(不清),坏死少见,钙化及出血罕见。Ki-67指数高低组间PPL的大小及边界差异有统计学意义(χ~2=4.211,P=0.040;χ~2=11.555,P=0.001),余CT征象差异无统计学意义(P>0.05)。15例PPL患者5年生存率为66﹪,仅与肿瘤的Ki-67指数表达的高低(χ~2=4.454,P=0.035)显著相关,与各CT征象无显著相关性(P>0.05)。结论腮腺原发性淋巴瘤CT表现具有一定的特征性,Ki-67表达水平高低组间在大小、边界上存在一定差异。腮腺原发性淋巴瘤预后较好,与肿瘤的Ki-67密切相关。 Objective To investigate the features in CT images of parotid primary lymphoma(PPL), and study their relationship with Ki-67 index and prognosis. Methods Thirty-seven cases of PPL confirmed by pathology were retrospectively collected, and the CT images were analyzed. The relationship between image features(size, location, shape, boundary and enhancement degree)and Ki-67 index was analyzed by performing a chi-square test, the survival rate of 15 cases with PPL was calculated by Kaplan-Meier method, and a survival analysis considering gender, age, CT image features(lesion location, lesion imaging morphology, borderlines, enhancement mode)and Ki-67 PI was performed using the Log-Rank test. Results PPL with MALTL(marginal B-cell lymphoma)and FL(follicular lymphoma)were more common, and the CT mostly showed multiple nodules or diffuse nodules, with moderate to severe uniform enhancement, clear or unclear borders;necrosis, calcification and hemorrhage was rarely found. Significant differences were foundin the size and boundary of PPL between the high and low Ki-67 groups(χ^2 = 4.211, P = 0.040;χ^2 = 11.555, P = 0.001), and no significant difference in the residual CT features(P > 0.05). The 5-year survival rate of 15 patients with PPL was 66 ﹪,which was only significantly correlated with the expression of the Ki-67 index(χ^2 = 4.454, P = 0.035), and had no significant correlation with the CT features(P > 0.05). Conclusion CT findings of PPL have certain characteristics. There are some differences in size and boundary between high and low Ki-67 index groups. The prognosis of PPL is good, which is closely related to the Ki-67 index.
作者 刘国顺 李雯曦 谭相良 郭媛 黎蕾 谌丹丹 熊炜烽 江新青 LIU Guoshun;LI Wenxi;TAN Xiangliang;GUO Yuan;LI Lei;CHEN Dandan;XIONG Weifeng;JIANG Xinqing(Department of Radiology,Guangzhou First People’s Hospital,the SecondAffiliated Hospital of South China University of Technology,Guangzhou 510180,China)
出处 《功能与分子医学影像学(电子版)》 2018年第3期1498-1505,共8页 Functional and Molecular Medical Imaging(Electronic Edition)
关键词 淋巴瘤 腮腺 CT表现 KI-67指数 预后 lymphoma parotid gland CT manifestation Ki-67 index prognosis
  • 相关文献

参考文献4

二级参考文献33

共引文献16

同被引文献21

引证文献3

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部