摘要
目的通过Meta分析了解中国40岁及以上人群翼状胬肉患病率情况。方法检索1990—2016年在中国生物医学文献数据库(CBMdisc)、中国期刊全文数据库(CNKI)、维普数据库(VIP)、万方数据库、PubMed、荷兰医学文摘数据库(EMBASE)、WebofScience收录的有关中国地区翼状胬肉患病率研究的文献,采用美国卫生保健质量和研究机构(AHRG)推荐的横断面研究质量评价标准对纳入文献质量进行评价。采用Stata13.0软件进行患病率合并,并对年龄、性别及区域等因素进行亚组分析。结果纳入相关文献36篇,其中8篇英文,28篇中文)。采用随机效应模型合并36项研究数据,分析得出1990—2016年中国40岁及以上人群翼状胬肉患病率为13.4%[95%置信区间(CI):10.6%~16.5%)。亚组分析结果显示,随年龄增加翼状胬肉患病率升高;农村翼状胬肉患病率为15.3%(95%CI:12.1%~18.8%),高于城市的4.0%(95%CI:2.4%~6.1%)。调查对象为≥40岁农村人群翼状胬肉的患病率为12.1%(95%CI:8.6%~16.2%),调查对象为≥50岁农村人群翼状胬肉的患病率为14.7%(95%CI:10.5%~19.5%)。不同年龄和性别亚组各地区间翼状胬肉患病率均为西部最高,其次是东部,中部最低。结论翼状胬肉在中国40岁及以上人群中患病率较高,且翼状胬肉患病率在不同年龄及地区等因素间存在差异。
Objective To evaluated the prevalence of pterygium among people aged≥40 in China by using Meta analysis.Methods A literature retrieval was performed in China biology medicine disc(CBMdisc),China national knowledge infrastructure(CNKI),VIP database,WanFang database,PubMed,excerpta medica database(EMBASE),Web of Science from 1990 to 2016 according to designed searching strategy.Tailored quality evaluation standard of epidemiological research was used to evaluate the study quality of each included study.Stata 13.0 software was used to estimate the prevalence of pterygium,subgroup analysis of age,sex and region was also carried out.Results Thirty-six studies were involved in this Meta analysis,including 8 English researches and 28 Chinese researches.The random effect model was used to merge 36 research data.The prevalence of pterygium among people aged over 40 in China was 13.4%[95% confidence interval(CI):10.6%-16.5%].Subgroup analysis results showed that the prevalence of pterygium increased with age.The prevalence of pterygium in rural region was 15.3%(95% CI:12.1%-18.8%),which was higher than 4.0%(95% CI:2.4%-6.1%)in urban region.The prevalence of pterygium among rural people aged≥40 was 12.1%(95% CI:8.6%-16.2%),which was lower than 14.7%(95% CI:10.5%-19.5%)among rural people aged≥50.The highest prevalence of pterygium in different age and sex subgroups was in the west region of China,followed by the east region of China and the lowest was in the central region of China.Conclusion The prevalence of pterygium among people aged≥40 in China was high.Over the past decade,the prevalence of pterygium were different among different ages,and places of residence.
作者
杨梅
管宇
康丽华
秦柏
张俊芳
Yang Mei;Guan Yu;Kang Lihua;Qin Bai;Zhang Junfang(Department of Ophthalmology,Affiliated Hospital of Nantong University,Nantong 226001,China)
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2019年第3期190-196,共7页
Chinese Journal Of Experimental Ophthalmology
基金
江苏省预防医学研究课题项目(Y2018095).
