摘要
目的:观察自拟"消癜方"联合左西替利嗪治疗过敏性紫癜的临床效果。方法:将72例过敏性紫癜患者随机分为对照组和治疗组各36例。对照组给予常规治疗,观察组在此基础上给予自拟"消癜方"治疗,每日1剂,两组疗程均为14d。比较两组患者皮肤紫癜及其他症状(腹痛、关节痛)消退时间、血清免疫球蛋白水平、临床疗效和复发情况。结果:治疗后,治疗组皮肤紫癜及其他症状(腹痛、关节痛)消退时间明显短于对照组,差异有统计学意义(P <0.05);治疗组免疫球蛋白IgA水平明显下降,较对照组下降更为显著,差异有统计学意义(P <0.05)。治疗组总有效率为97.22%,对照组总有效率为83.33%,治疗组的总有效率明显优于对照组,差异有统计学意义(P <0.05)。治疗组复发1例,复发率为2.78%,对照组复发7例,复发率为19.44%,治疗组复发率明显低于对照组,差异有统计学意义(P <0.05)。结论:自拟"消癜方"联合左西替利嗪治疗过敏性紫癜,不仅能有效缓解患者的临床症状,还可调整平衡患者免疫功能,减少复发。
Objective: To observe curative effects of the Xiaodian decoction plus levocetirizine on allergic purpura. Methods: 72 patients with allergic purpura were randomly divided into two groups, 36 cases in each. The control group was given conventional treatment, and the observation group was given the Xiaodian decoction more. The regression time of purpura and other symptoms (abdominal pain, joint pain), serum immunoglobulin levels, clinical efficacy and recurrence in two groups were compared. Results: The regression time of purpura and other symptoms (abdominal pain, joint pain) in the control group was significantly shorter than that in the control group ( P < 0.05). The level of IgA in the treatment group was significantly decreased and significantly lower than the control group ( P < 0.05). The total effective rate in the treatment group was 97.22%, significantly better than 83.33% in the control group ( P <0.05). The recurrence rate in the treatment group was 2.78%, significantly lower than 19.44% in the control group ( P <0.05). Conclusion: The Xiaodian decoction plus levocetirizine can effectively relieve the clinical symptoms and can also adjust the immune function to reduce the recurrence.
出处
《中医临床研究》
2019年第4期61-63,共3页
Clinical Journal Of Chinese Medicine
