摘要
目的探讨儿童肺炎支原体肺炎合并基底动脉尖综合征的临床特点。方法回顾分析1例肺炎支原体肺炎合并基底动脉尖综合征患儿的临床资料,并复习相关文献。结果女性患儿,6岁,以发热、单侧肢体活动不灵活起病。血清肺炎支原体抗体逐次升高;肺部CT提示大片炎性实变;头颅MRI示多发性脑梗死。给予抗感染及抗凝、溶栓、降颅压等综合对症治疗后,患儿病情仍进行性加重,出现昏迷、咳嗽无力、吞咽困难、面神经麻痹、双瞳孔不等大。患儿虽生命体征平稳,但生活不能自理,仍在康复中。结论肺炎支原体肺炎常伴有高凝状态及自身免疫异常,并发基底动脉尖综合征者预后差。
Objective To explore the clinical characteristics of Mycoplasma pneumoniae pneumonia(MPP) complicated with "top of the basilar" syndrome(TOBS) in children. Method The clinical data of MPP complicated with TOBS in a child were retrospectively analyzed, and the related literature was reviewed. Results A 6-year-old girl developed fever and inflexible movement in unilateral limb, and serum Mycoplasma pneumoniae antibody increased gradually. Lung CT showed a large area of inflammatory consolidation. Brain magnetic resonance imaging(MRI) showed multiple cerebral infarctions. After the symptomatic treatment of anti-infection, anticoagulation, thrombolysis and intracranial pressure reduction, the girl’s condition continued to worsen and she presented with coma, cough weakness, dysphagia, facial nerve paralysis and bilateral pupillary inequality. Although the vital signs of the child were stable, she could not take care of herself and was still recovering. Conclusion MPP is often accompanied by hypercoagulative state and autoimmune abnormalities, and the prognosis of patients combined with TOBS is poor.
作者
王欣
杨花芳
王唯一
郑华城
WANG Xin;YANG Huafang;WANG Weiyi;ZHENG Huacheng(Department of Neurology,Hebei Children's Hospital,Shijiazhuang 050031,Hebei,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2019年第1期34-38,共5页
Journal of Clinical Pediatrics
基金
河北省医学科学研究重点课题计划(No.20160424)
关键词
肺炎支原体肺炎
基底动脉尖综合征
儿童
Mycoplasma pneumoniae pneumonia
top of the basilar syndrome
child
