摘要
目的本研究旨在分析老年乳腺癌患者的临床病理特点和治疗现状,为进一步开展相关临床研究与治理提供依据。方法收集某三甲医院2005年1月至2010年3月所有≥65岁的经病理确诊的老年乳腺癌患者,将其分为<70岁组和≥70岁组两组,分析两组老年乳腺癌患者在基本临床情况、生殖风险、病理情况和治疗情况的特点。结果老年乳腺癌患者高发年龄为70岁,体质指数为24.3,教育程度以高中以下为主。≥70岁组老年患者较<70岁组老年患者活产次数高(P<0.05),但淋巴结转移较低(P <0.05)。乳腺癌的病理类型在两组老年患者中差别没有统计学意义(P> 0.05)。两组老年患者目前化学治疗、放射治疗、内分泌治疗和手术治疗仍存在不规范,内分泌治疗、靶向治疗和保乳手术治疗开展的仍然不足。结论目前我国老年乳腺癌仍存在不规范治疗,化疗、内分泌治疗、靶向治疗和手术治疗仍需进一步规范化。应积极开展老年乳腺癌患者临床规范化治疗、推进保乳手术、内分泌治疗和靶向治疗在老年乳腺癌患者中的应用。进一步加强医师培训,促进规范化治疗,并扩展保乳手术、内分泌治疗和靶向治疗的应用。
Objective This study aimed to investigate the clinical characteristics and treatment status among aged breast cancer patients in order to provide evidence for further research.Methods Aged breast cancer patient(≥65)were received in a local hospital from January 2005 to March 2010,divided into two groups,<70 and≥70 years old.Data including basic information,reproductive risk factors,pathological characters and treatment management were collected from medical records.The comparison was conducted between aged patients of<70 and≥70 years old.Results The mean age of included patients was 70.The average BMI was 24.3.Most of patients received education below tertiary high school.The patients of≥70 were more likely to have more living births(P<0.05)but lower lymph node metastasis(P<0.05).The pathological types were not statistically significant in the two groups(P >0.05).Currently chemotherapy,endocrine-therapy,surgery were still processed non-standardized.Endocrine-therapy,target therapy and breast conservative surgery was still applied inadequately.Conclusions The standardized treatment among aged breast cancer patients needed be strengthened.Chemotherapy,endocrinology,targeted therapy and surgical treatment still need to be further normalized.Breast conservation surgery,endocrine therapy and target therapy should be promoted for more application.
作者
伍江平
孙晓彤
王京
李雨晨
赵琳
WU Jiang-ping;SUN Xiao-tong;WANG Jing;LI Yu-chen;ZHAO Lin(Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;Beijing Tsinghua Changgung Hospital,Beijing102218,China;Beijing Chaoyang Hospital (Beijing West Campus) Affiliated to Capital medical university,Beijing 100043,China;Xuanwu Hospital Affiliated to Capital Medical University,Beijing 100053,China)
出处
《肿瘤代谢与营养电子杂志》
2018年第4期387-390,共4页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
北京市科委首都市民健康项目培育(Z161100000116066)
首都医科大学基础临床研究课题(15JL87)
关键词
老年乳腺癌
病理特点
治疗现状
Aged breast cancer
Pathological characteristics
Clinical treatment
