摘要
目的比较甲氨蝶呤联合宫腔镜电切术与清宫术治疗Ⅰ型瘢痕妊娠的临床疗效。方法选取52例彩色多普勒超声诊断的Ⅰ型瘢痕妊娠患者根据手术方式分为2组,一组为观察组,采用甲氨蝶呤联合宫腔镜电切术;另一组为对照组,采用甲氨蝶呤联合清宫术治疗。观察比较两组患者的血清β-HCG下降至正常水平的时间、手术时间、住院时间、术中出血量及恢复正常月经时间及术后不良及并发症的情况。结果两组患者均顺利完成手术,均未出现因大流血而子宫切除的情况。观察组患者的血清β-HCG水平下降至正常水平的时间、手术时间、住院时间及月经恢复正常时间均低于对照组(P<0.05),观察组术中出血量明显低于对照组(P<0.05),差异有统计学意义。观察组不良及并发症发生率低于对照组(P<0.05),差异有统计学意义。结论甲氨蝶呤联合宫腔镜电切术治疗瘢痕妊娠成功率高,恢复快,术中出血少,不良反应少,有利于保留子宫及生育功能,疗效满意。
OBJECTIVE To compare the clinical efficacy of methotrexate combined with hysteroscopic electrocision and curettage in the treatment of type I scar pregnancy.METHODS 52 cases of cicatricial pregnancy diagnosed by color Doppler ultrasound were divided into 2 groups according to the operation mode,one group was the observation group,using the methotrexate combined with hysteroscopy in the treatment,and the other group was treated with methotrexate combined hysteroscopy.The time of the decrease of serum beta-HCG to the normal level,the time of operation,the time of hospitalization,the amount of bleeding in the operation,the recovery of normal menstruation,the postoperative complications and complications were observed and compared between the two groups.RESULTST wo groups of patients successfully completed the operation.There was no case of hysterectomy due to massive bleeding.The level of serum beta-HCG in the observation group was lower than the control group(P<0.05),and the amount of bleeding in the observation group was significantly lower than that of the control group(P<0.05).The difference was statistically significant.The incidence of bad and complications in the observation group was lower than that in the control group(P<0.05),and the difference was statistically significant.CONCLUSION Methotrexate combined with hysteroscopy in the treatment of cicatricial pregnancy had high success rate,rapid recovery,less bleeding and less adverse reactions in the operation,which was beneficial to the retention of uterus and reproductive function.
作者
曹成芳
CAO Cheng-fang(Qingyuan Manchu Autonomous County Hospital of Traditional Chinese Medicine,Fushun,Liaoning,113300,China)
出处
《中国初级卫生保健》
2019年第2期43-44,共2页
Chinese Primary Health Care
关键词
甲氨蝶呤
瘢痕妊娠
宫腔镜电切术
清宫术
methotrexate
scar pregnancy
hysteroscopic electrocision
curettage
