摘要
目的研究并分析长期应用糖皮质激素治疗对支气管哮喘患儿生长发育的影响。方法本院在2014年2月至2016年2月收治的支气管哮喘患儿中选择40例进行治疗,所有患儿均接受2年的糖皮质激素治疗,并设为观察组。另选择40例健康体检儿童作为对照组。对两组儿童的身高、体质量、骨密度等进行测定并对比。结果观察组患儿经2年治疗后总有效率为100.0%。该组患儿治疗后的ICG-1平均为(220.3±34.2)ng/L、LEP平均为(5.88±0.45)μg/L、BGP平均为(41.97±12.33)μg/L,与对照组相比差异无统计学意义。治疗后该组患儿的平均身高增长(16.5±3.5)cm,体质量平均增长(2.2±0.4)kg,与对照组比较差异无统计学意义。结论长期规范化的应用糖皮质激素为支气管哮喘患儿进行临床治疗并不会对患儿的生长发育造成明显影响。
Objective To study and analyze the long-term effects of glucocorticoid therapy on the growth and development of children with bronchial asthma. Methods A total of 40 children with bronchial asthma admitted to our hospital from February 2014 to February 2016 were selected.All the children were treated with glucocorticoid for 2 years and served as the observation group. In addition, 40 healthy children were selected as the control group. The height, weight and bone mineral density of two groups of children were measured and compared. Results The total effective rate of the observation group was 100.0% after 2 years of treatment. The average ICG-1 after treatment in this group was (220.3±34.2) ng/L, LEP was (5.88±0.45) g/L and BGP was (41.97±12.33) g/L, which was not significantly different from that of the control group. After treatment, the average height growth of the group was (16.5±3.5) cm, the average body mass increased (2.2±0.4) kg, and the difference was not significant compared with the control group. Conclusion The long-term standardized application of glucocorticoids for children with bronchial asthma has no obvious effect on the growth and development of children.
作者
白鹏
高岳
Bai Peng;Gao Yue(The Department of paediatrics of General Hospital of Jinlin Oil Field, Songyuan, Jilin, 138000, China;The Department of Respiration of Changchun Children' s Hospital, Changchun, Jilin, 130000, China)
出处
《当代医学》
2019年第8期94-96,共3页
Contemporary Medicine
关键词
长期应用
糖皮质激素
支气管哮喘
生长发育
Long term application
Glucocorticoid
Bronchial asthma
Growth and development
