摘要
目的探讨血清学化验指标预测Le,g型食管胃静脉曲张患者行改良三明治法联合套扎治疗术后静脉曲张复发风险的价值。方法纳入于我院住院并行内镜下改良三明治法同步联合套扎治疗的Le,g型食管胃静脉曲张患者60例。术后2周、3个月、6个月复查电子胃镜,根据胃镜复查结果分为有EGV复发及再出血组(A组,38例)和无EGV复发及再出血组(B组,22例)。比较两组患者APRI、AAR、FIB-4及RPR数值差异。结果 A组APRI为3.33±0.51、FIB-4为8.36±0.92、RPR值为0.38±0.17均明显高于B组(2.37±0.57、5.80±1.34、0.23±0.11),差异有统计学意义(P<0.05),但两组AAR值差异无统计学意义(P>0.05)。APRI、FIB-4、RPR预测Le,g型食管胃静脉曲张患者行改良三明治法同步联合套扎治疗术后曲张静脉复发及再出血风险曲线下面积分别为0.800、0.934、0.741;诊断界值分别为0.496、0.804、0.344,灵敏度分别为63.2%、89.5%、52.6%,特异度分别为86.4%、90.9%、81.8%。结论无创血清学APRI、FIB-4、RPR指数有助于评估改良三明治法同步联和套扎治疗Le,g型EGV患者术后EGV复发及再出血的风险。
Objective To study the predictive value of serum index in the evaluation of postoperative varices recurrence risk for patients with Le,g type esophageal and gastric variceal in modified sandwich method with ligation. Methods 60 cases of Le,g type esophageal and gastric variceal patients in our hospital treated with the modified sandwich method and combined with synchronization ligation were enrolled. The gastroscopy was performed two weeks, three and six months after endoscopic treatment. All patients were distributed to the group A (38 cases) and group B (22 cases) according to the results of gastroscopy. The differences of APRI,AAR,FIB-4 and RPR between two groups were compared. Results The APRI, FIB-4, RPR index of group A was respectively 3.33±0.51, 8.36±0.92, 0.38±0.17, which was significantly higher than group B (2.37±0.57,5.80±1.34,0.23±0.11),but the AAR index had no statistical difference(P >0.05). The area of the APRI, FIB-4 and RPR for predicting the risk of variceal recurrence or rebleeding after endoscopic treatment in patients with Le,g type EGV was 0.800,0.934,0.741 respectively, and the best diagnostic boundary was 0.496,0.804,0.344 respectively. The sensitivity was 63.2%, 89.5%,52.6% respectively. The specificity was 86.4%,90.9%,81.8% respectively. Conclusion Non-invasive serology APRI, FIB-4, and RPR indices can help to evaluate the risk of variceal recurrence after endoscopic treatment in patients with Le,g type EGV.
作者
林海
马士兰
张健
Lin Hai;Ma Shilan;Zhang Jian(Linyi Central Hospital, Linyi 276400)
出处
《中国现代医药杂志》
2019年第1期16-19,共4页
Modern Medicine Journal of China
关键词
无创血清学指数
Le
g型食管胃静脉曲张
改良三明治法
复发
Non-invasive serum index
Le,g type esophageal and gastric variceal
modified sandwich method
recurrence
