摘要
目的探讨2型糖尿病并发细菌性肝脓肿患者的临床特点与生存状况。方法前瞻性选择43例2型糖尿病并发细菌性肝脓肿患者设为合并组,另选择同期就诊的86例2型糖尿病患者设为糖尿病组,收集并对比2组患者的一般情况、临床表现等资料,并比较白细胞计数(WBC)、红细胞计数(RBC)、白蛋白(Alb)、中性粒细胞比例(NEUT%)、C反应蛋白(CRP)、纤维蛋白原(FIB)实验室指标,统计患者出院后1年的生存状况并计算总病死率。结果 2组患者畏寒或寒战、腹胀、咳嗽或咳痰、肝区叩痛及肝区压痛的比例有显著差异(P<0.05),右上腹痛、发热、黄疸、恶心或呕吐、体质量下降的比例差异无统计学意义(P>0.05)。合并组Alb为(24.19±10.39) g/L,显著低于糖尿病组(32.55±11.46) g/L;合并组NEUT%为(86.61±23.46)%、CRP为(140.69±31.65) mg/L,分别显著高于糖尿病组(74.18±20.11)%、(23.17±9.67) mg/L(P<0.05)。合并组1年随访期间总病死率为16.28%,显著高于糖尿病组2.33%(P<0.05)。结论 2型糖尿病并发细菌性肝脓肿患者的临床特点为畏寒或寒战、腹胀、咳嗽或咳痰、肝区叩痛及肝区压痛,临床医师应争取早期诊断,且2型糖尿病患者并发细菌性肝脓肿时Alb、NEUT%、CRP指标变化显著,病死率也高于单纯糖尿病患者。
Objective To explore the clinical characteristics and survival status of patients with type 2 diabetes mellitus complicated with bacterial liver abscess.Methods A total of 43 patients with type 2 diabetes mellitus complicated with bacterial liver abscess in our hospital were selected as combination group,another 86 patients with type 2 diabetes in our hospital were selected as diabetes group at the same time.General information,and clinical symptoms were compared,and the laboratory indexes in terms of leukocyte count(WBC),red blood cell count(RBC),albumin(Alb),proportion of medium line granulocyte count(NEUT%),C reactive protein(CRP),fibrinogen(FIB)were compared.The total mortality and 1-year survival rates after discharge were statistically analyzed.Results Significant difference of two groups was observed in chill or chills,abdominal distention,cough or expectoration,tap pain in liver(P<0.05).The patients with right upper abdominal pain,fever,jaundice,nausea or vomiting,and body mass showed no significant difference(P>0.05).The Alb index was(24.19±10.39)g/L in the combined group,which was significantly lower than(32.55±11.46)g/L of the diabetic group,NEUT and CRP in combined group were(86.61±23.46)%,(140.69±31.65)mg/L,respectively,which were significantly higher than(74.18±20.11)%,(23.17±9.67)mg/L in diabetic group(P<0.05).The total mortality rate of the combined group during 1-year follow-up period was 16.28%,which was significantly higher than 2.33%in the diabetic group(P<0.05).Conclusion The clinical characteristics of type 2 diabetes mellitus complicated with bacterial liver abscess are cold or shivering,abdominal distention,cough or expectoration,liver District tapping and liver pain.Therefore,physicians should make early diagnosis.The type 2 diabetes mellitus patients has obvious changes of Alb,NEUT%,NEUT and CRP,and higher mortality rate.
作者
王金华
潘建新
杨为霞
WANG Jinhua;PAN Jianxin;YANG Weixia(Endocrine Department Dachang Hospital of Baoshan District in Shanghai,Shanghai,200444;Department of Traditional Chinese Medicine,Dachang Hospital of Baoshan District in Shanghai,Shanghai,200444)
出处
《实用临床医药杂志》
CAS
2019年第3期82-84,92,共4页
Journal of Clinical Medicine in Practice
关键词
2型糖尿病
细菌性肝脓肿
临床特点
生存率
病死率
type 2 diabetes
bacterial liver abscess
clinical characteristics
survival rate
mortality rate
