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冠脉CTA评估心绞痛患者斑块性质及其与心血管事件的相关性研究 被引量:15

Plaque Properties of Patients with Angina Pectoris Evaluated by Coronary CTA and Their Correlation with Cardiovascular Events
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摘要 目的探究冠状动脉(冠脉)电子计算机断层扫描血管造影(CTA)评估心绞痛患者斑块性质及其与心血管事件的相关性。方法回顾性分析我院216例心绞痛患者相关资料,并根据其临床资料分为稳定型心绞痛组(SAP组,78例)及非稳定型心绞痛组(UAP组,138例)。比较两组斑块性质差异,并分析两组心血管事件发生情况与斑块性质的相关性。结果 SAP组斑块以钙化斑块为主;UAP组则以软斑块为主;两组混合斑块率比较,差异无统计学意义(P>0.05);SAP组软斑块率明显低于UAP组(P<0.05),钙化斑块率则高于UAP组(P<0.05)。SAP组共发生8例心血管事件(10.26%),UAP组共发生心血管事件41例(29.71%);且两组组内发生心血管事件与未发生心血管事件患者混合斑块率比较,差异均无统计学意义(P>0.05);组内发生心血管事件患者软斑块率明显高于未发生心血管事件患者(P<0.05),而钙化斑块率低于未发生心血管事件患者(P<0.05)。结论软斑块与心绞痛患者发生心血管事件关系密切,而冠脉CTA能有效评估斑块性质,对辅助预测患者预后情况有一定作用。 Objective To explore the plaque properties of patients with angina pectoris evaluated by coronary computerized tomography angiography(CTA)and their correlation with cardiovascular events.Methods The related data of 216 patients with angina pectoris in our hospital were analyzed retrospectively.According to the clinical data,they were divided into stable angina pectoris group(SAP group,78 cases)and unstable angina pectoris group(UAP group,138 cases).The differences in plaque properties were compared between the two groups,and the correlation between cardiovascular events and plaque properties was analyzed.Results The plaques were mainly calcified plaques in SAP group,and were soft plaques in UAP group.There was no statistically significant difference in the rate of mixed plaques between the two groups(P>0.05).The soft plaques rate in SAP group was significantly lower than that in UAP group(P<0.05)while the calcified plaques rate was higher than that in UAP group(P<0.05).There were 8 cases(10.26%)of cardiovascular events in SAP group and were 41 cases(29.71%)of cardiovascular events in UAP group.There was no significant difference in the mixed plaques rate between patients with cardiovascular events and patients without cardiovascular events within the two groups(P>0.05).The soft plaques rate in patients with cardiovascular events was significantly higher than that in patients without cardiovascular events(P<0.05),but the calcified plaques rate was lower than that in patients without cardiovascular events(P<0.05).Conclusion Soft plaque is closely related to cardiovascular events in patients with angina pectoris.Coronary CTA can effectively evaluate the plaque properties and play a role in predicting the prognosis of patients.
作者 郭长磊 GUO Chang-lei(Department of Cardiology,First Affiliated Hospital of Xinxiang Medical College,Xinxiang 453100,Henan Province,China)
出处 《中国CT和MRI杂志》 2018年第12期62-64,共3页 Chinese Journal of CT and MRI
基金 河南省卫生厅资助基金项目(No.201303105)
关键词 CTA 冠状动脉 斑块性质 心绞痛 心血管事件 CTA Coronary Artery Plaque Properties Angina Pectoris Cardiovascular Events
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