摘要
目的探讨参附注射液对急性心肌梗死患者心功能的影响。方法选取2016年3月-2017年3月在我院确诊为急性心肌梗死患者58例,按随机数字法分为两组,29例患者给予常规治疗为常规组,29例患者给予常规治疗+参附注射液治疗为探究组,观察两组疗效。结果探究组的总有效率(79.31%)高于常规组(51.72%)(P<0.05);两组治疗后CI、CO、LVEF指标均高于治疗前,HR指标低于治疗前,差异显著(P<0.05);探究组心功能各指标改善效果优于常规组(P<0.05);两组治疗后TNF-α、CPR指标均低于治疗前,NO指标高于治疗前,差异显著(P<0.05);探究组TNF-α、CPR及NO水平改善幅度显著于常规组(P<0.05);两组均未见明显不良反应。结论参附注射液可有效改善急性心肌梗死患者心功能,降低炎症反应,临床治疗安全有效。
Objective To explore the effects of Shenfu injection on cardiac function in patients with acute myocardial infarction.Methods 58 patients with acute myocardial infarction diagnosed in our hospital from March 2016 to March 2017 were selected and divided into two groups according to the random number table method.29 cases given routine treatment were taken as routine group,and 29 cases treated with routine treatment+Shenfu injection were selected as study group.The efficacy of the two groups was observed.Results The total effective rate in study group was significantly higher than that in routine group(79.31%vs 51.72%)(P<0.05).After treatment,the indexes of CI,CO and LVEF in the two groups were higher than those before treatment while the index of HR was significantly lower than that before treatment(P<0.05).The improvements of cardiac function in study group were better than those in routine group(P<0.05).After treatment,the indexes of TNF-αand CPR in the two groups were lower than those before treatment while the index of NO was higher than that before treatment(P<0.05).The improvements of TNF-α,CPR and NO in study group were significantly better than those in routine group(P<0.05),and there were no obvious adverse reactions in the two groups.Conclusion Shenfu injection can effectively improve the cardiac function of patients with acute myocardial infarction and reduce the inflammatory responses,and its clinical treatment was safe and effective.
作者
陈亚君
乔雯
CHEN Ya-jun;QIAO Wen(Department of Cardiology,The First Affiliated Hospital of Henan Polytechnic University,Jiaozuo 454000,Henan Province,China)
出处
《罕少疾病杂志》
2018年第6期11-13,共3页
Journal of Rare and Uncommon Diseases
关键词
参附注射液
急性心肌梗死
心功能
Shenfu Injection
Acute Myocardial Infarction
Cardiac Function
