摘要
目的:探讨根据血清铁蛋白及血红蛋白水平给予孕妇预防性补铁对妊娠期铁缺乏、贫血、妊娠并发症及妊娠结局的影响。方法:选择300例单胎孕妇为研究对象,分为试验组和对照组,试验组同时监测血红蛋白及血清铁蛋白,当血清铁蛋白<30μg/L时给予预防性口服补铁73. 6 mg/d,对照组监测血红蛋白,当血红蛋白<110 g/L时给予治疗性口服补铁220. 8 mg/d,比较两组孕妇产前血清铁蛋白、血红蛋白水平,铁缺乏、贫血发生率、补铁后不良反应发生率、妊娠期糖尿病、妊娠期高血压疾病发生率、早产、低出生体重儿、产后出血、产后贫血发生率。结果:截至分娩前,试验组孕妇的血清铁蛋白、血红蛋白水平显著高于对照组,差异有统计学意义(P <0. 05),试验组孕妇的铁缺乏、贫血发生率显著低于对照组,差异有统计学意义(P <0. 05),试验组补铁后不良反应发生率显著低于对照组,差异有统计学意义(P<0. 05)。两组孕妇妊娠期糖尿病、妊娠期高血压疾病、早产、低出生体重儿、产后出血的发生率差异无统计学意义(P>0. 05),试验组孕妇产后贫血的发生率显著低于对照组,差异有统计学意义(P <0. 05)。结论:孕期根据血清铁蛋白及血红蛋白水平给予孕妇预防性补铁对增强孕妇补铁依从性、降低孕期铁缺乏、产前产后贫血发生率有明显效果。
Objective To explore the influence of preventive iron supplementation according to serum ferritin and hemoglobin levels during pregnancy on iron deficiency,anemia,pregnancy complications and pregnancy outcome.Method In this experiment,300 pregnancy women were enrolled and divided into experimental group and control group.Hemoglobin and serum ferritin were also monitored in the experimental group.Oral iron supplementation was given 73.6 mg/d when serum ferritin was less than30μg/L.Hemoglobin was monitored in the control group.Oral iron supplementation was given 220.8 mg/d when hemoglobin was less than 110 g/L.The levels of serum ferritin and hemoglobin,the incidence of iron deficiency and anemia,the incidence of adverse reactions,gestational diabetes mellitus and pregnancy induced hypertension,premature delivery,low birth weight infants,postpartum hemorrhage and postpartum anemia were compared between the two groups.Results Before delivery,the levels of serum ferritin and hemoglobin in the experimental group were significantly higher than those in the control group(P<0.05),the incidence of iron deficiency and anemia in the experimental group were significantly lower than those in the control group(P<0.05),and the incidence of adverse reactions in the experimental group was significantly lower than that in the control group(P<0.05).There was no significant difference in the incidence of gestational diabetes mellitus,gestational hypertension,premature delivery,low birth weight infants and postpartum hemorrhage between the two groups(P >0.05).The incidence of postpartum anemia in the experimental group was significantly lower than that in the control group(P<0.05).Conclusion Preventive iron supplementation according to the levels of serum ferritin and hemoglobin during pregnancy has a significant effect on enhancing the compliance of pregnant women with iron supplementation,reducing iron deficiency during pregnancy and the incidence of prenatal and postpartum anemia.
作者
李占辉
阮冀
LI Zhan-hui;RUAN Ji(Department of obstetrics and Gynecology,Beijing Fengtai Hospital Integrated of Traditional and Western Medicine,Beijing 100072,China)
出处
《吉林医学》
CAS
2019年第2期220-222,共3页
Jilin Medical Journal
关键词
血清铁蛋白
血红蛋白
预防性补铁
孕期
Serum ferritin
Hemoglobin
Preventive iron supplementation
Pregnancy
