摘要
目的观察针灸治疗过敏性鼻炎的疗效及对患者生活质量的影响。方法选择过敏性鼻炎患者72例,采用随机数字表法分为对照组和观察组,每组36例。对照组采用常规西药治疗,观察组采用针灸治疗,两组均连续治疗3个月,治疗完毕后对效果进行评估。采用酶联免疫吸附试验测定VCAM-1、白细胞介素-4(IL-4)、白细胞介素-6(IL-6)及白细胞介素-10(IL-10)水平;采用WHOQOl-BREF生活量表对两组生活质量进行评估,比较两组临床疗效及对患者生活质量的影响。结果观察组总有效率为97.2%,高于对照组的86.1%(P<0.05);两组治疗前VCAM-1、IL-4、IL-6及IL-10水平比较差异无统计学意义(P>0.05);观察组和对照组治疗后VCAM-1、IL-4、IL-6及IL-10水平均低于治疗前(P<0.05);观察组治疗后VCAM-1、IL-4、IL-6及IL-10水平均低于对照组(P<0.05);观察组和对照组治疗后生理健康、心理状态、社会关系、周围环境、独立能力评分均高于治疗前(P<0.05);观察组治疗后生理健康、心理状态、社会关系、周围环境、独立能力评分均高于对照组(P<0.05)。结论针灸治疗过敏性鼻炎疗效确切,能降低炎症因子水平,改善患者生活质量。
Objective To investigate the therapeutic effect of acupuncture and moxibustion on allergic rhinitis and its influence on the patients’quality of life.Method Seventy-two patients with allergic rhinitis were allocated,according to different protocols,to control and observation groups,36 cases each.The control group received conventional Western drug treatment and the observation group,acupuncture and moxibustion.Both groups were treated for three consecutive months.The effects were evaluated after the completion of treatment.VCAM-1,interleukin-4(IL-4),interleukin-6(IL-6)and interleukin-10(IL-10)levels were measured using enzyme linked immunosorbent assay.The quality of life was assessed using the WHOQOL-BREF.The clinical therapeutic effects and the influences on the patients’quality of life were compared between the two groups.Result The total efficacy rate was 97.2%in the observation group,which was higher than 86.1%in the control group(P<0.05).There were no statistically significant pre-treatment differences in VCAM-1,IL-4,IL-6 and IL-10 levels between the two groups(P >0.05).After treatment,VCAM-1,IL-4,IL-6 and IL-10 levels decreased in both observation and control groups compared with before(P<0.05)and were lower in the observation group than in the control group(P<0.05).After treatment,the physical health,psychological health,social relationships,environment and independent ability scores increased in both observation and control groups compared with before(P<0.05)and were higher in the observation group than in the control group(P<0.05).Conclusion Acupuncture and moxibustion has a definite therapeutic effect on allergic rhinitis.It can reduce the levels of inflammatory factors and improve the patients’quality of life.
作者
贾旭锦
熊逸群
王佳艳
JIA Xu-jin;XIONG Yi-qun;WANG Jia-yan(Ningbo Hospital of Traditional Chinese Medicine,Ningbo 315010,China;Ningbo Yinzhou Second Hospital,Ningbo 315010,China)
出处
《上海针灸杂志》
2019年第2期202-205,共4页
Shanghai Journal of Acupuncture and Moxibustion
关键词
针灸疗法
隔姜灸
鼻炎
变应性
过敏性鼻炎
炎症因子
生活质量
酶联免疫吸附试验
Acupuncture-moxibustion therapy
Ginger moxibustion
Rhinitis,Allergic
Rhinallergosis
Inflammatory factor
Quality of life
Enzyme linked immunosorbent assay
