摘要
目的分析1500例行经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)的冠心病(coronary heart dis ease,CHD)患者预后的影响因素。方法选取本院2014年12月至2017年7月收治的1500例行PCI的冠心病患者为研究对象,按是否发生主要不良心脏事件(major adverse cardiac events,MACE)将其分为预后良好组和预后不良组,采用多因素Logistic回归分析探讨影响患者预后的因素。结果 1500例患者均完成1年随访,MACE发生率为16.00%。多因素Logistic回归分析显示:有冠心病家族史、合并糖尿病、左室射血分数、血细胞比容、平均红细胞体积、红细胞分布宽度、N末端B型利钠肽原、高敏C反应蛋白均是影响PCI患者预后的独立危险因素(P_均<0.05)。结论行PCI的患者术后MACE发生风险高,应高度重视合并相关危险因素者,积极预防,以最大限度地改善患者预后。
Objective To analyze the prognostic factors of 1500 patients with coronary heart disease(CHD)undergoing percutaneous coronary intervention(PCI).Method 1500 CHD patients who underwent PCI in our hospital from December 2014 to July 2017 were enrolled in the study,they were divided into good prognosis group and poor prognosis group according to the occurrence of major adverse cardiac events(MACE).Multivariate Logistic analysis was performed to analyze risk factors affecting the prognosis.Result All of 1500 patients completed one-year follow-up.The incidence of MACE was 16.00%.Multivariate Logistic analysis showed that family history of CHD,combined with diabetes mellitus,left ventricular ejection fraction(LVEF),hematocrit,mean corpuscular volume,red cell distribution width,N-terminal pro-B-type natriuretic peptide(NT-proBNP)and high sensitivity C-reactive proten(hs-CRP)were independent risk factors affecting the prognosis of patients underwent PCI(Pall<0.05).Conclusion Postoperative MACE in CHD patients undergoing PCI is at high risk,we should attach great importance to patients with associated risk factors and actively prevent them so as to improve the prognosis farthest.
作者
袁晓荣
欧阳辉
杨紫涓
YUAN Xiao-rong;OUYANG Hui;YANG Zi-juan(Department of Cardiovascular Medicine,Dazhou Central Hospital,Sichuan,Dazhou 635000,China)
出处
《中国医学前沿杂志（电子版）》
2019年第1期95-99,共5页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金
四川省医学会科研项目(Q150901)
