摘要
目的探讨儿童塑型性支气管炎(PB)病原学特点。方法回顾性分析南华大学附属郴州医院2012年1月至2018年3月确诊为PB患儿的病例资料,其中45例均已完善7种呼吸道病毒抗原检测、肺泡灌洗液肺炎支原体(MP)核酸检测或血MP抗体检测、灌洗液培养,对其病原学特点进行总结。结果 45例患儿纤维支气管镜下均可见一支或多支支气管开口痰栓阻塞,灌洗液均见树枝样物,病理检查均为纤维素性渗出物及炎性渗出。其中病原学检测MP 14例,甲型流感病毒(IFA)5例,乙型流感病毒(IFB)5例,腺病毒(AVD)5例,AVD合并呼吸道合胞病毒1例,细菌4例(IFA、IFB合并肺炎链球菌感染各1例),其余14例均未发现明确病原;治愈或好转出院45例。结论儿童PB病原中,MP感染占首位,流感病毒次之,其次是AVD感染和细菌感染。
Objective To explore the pathogenic characteristics of children with plastic bronchitis(PB).Methods Retrospective analysis of the children cases diagnosed with PB from January 2012 to March 2018 in Chenzhou Hospital of South China University,of these,45 patients had completed the detection of 7 respiratory virus antigens,the detection of Mycoplasma pneumoniae(MP)nucleic acid in alveolar lavage fluid or the detection of MP antibody in blood,and the culture of lavage fluid,its pathogenic characteristics were summarized.Results In 45 cases,one or more bronchial opening sputum plugs were seen under the fiber bronchoscope,and tree branches were seen in the lavage solution,cellulose exudate and inflammatory exudation were seen in the pathological examination.Among them,there were 14 cases of MP,5 cases of influenza A virus(IFA),5 cases of influenza B virus(IFB),5 cases of adenovirus(AVD),1 case of adenovirus combined with respiratory syncytial virus,and 4 cases of bacteria(1 case of IFA,1 case of IFB combined with pneumococcal infection respectively),no clear pathogens were found in the remaining 14 cases.All 45 cases were cured or improved.Conclusion In the children PB bronchitis,MP infection is the first,followed by influenza virus,AVD infection and bacterial infection.
作者
邝瑞军
范楚平
KUANG Ruijun;FAN Chuping(Chenzhou Hospital of South China University,Chenzhou,Hunan 423000,China).)
出处
《现代医药卫生》
2019年第3期374-376,380,共4页
Journal of Modern Medicine & Health
