摘要
细菌是引起疾病感染最常见的病原体,不同种类细菌可产生一些挥发性有机化合物,其中一些潜在标志物可达到细菌鉴别的目的。现总结分析三种常见细菌(铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌)的潜在挥发性有机化合物的生物标志物和不同种类细菌之间的相同产物,以达到鉴别的目的。同时简要叙述了此三种细菌常见应用色谱、质谱检测技术原理及优缺点,并对未来细菌挥发性有机化合物分析方法发展进行了展望。
Bacteria are the most common pathogens causing disease infection.Different kinds of bacteria can produce some volatile organic compounds,of which some potential markers may be used for bacterial identification.In this paper,we summarized the potential volatile biomarkers of three common bacteria,including Pseudomonas aeruginosa,Escherichia coli and Staphylococcus aureus,and the same volatile organic compounds among different kinds of bacteria for the purpose of identification.Meanwhile,the principles,advantages and disadvantages of the gas chromatography(GC)and mass spectrometry(MS)detection techniques for these three bacteria were introduced,and the development prospects were also made of the analysis methods for the volatile organic compounds in bacteria.
作者
聂茅毛
李明娟
郭雷
刘德胜
李恩有
NIE Maomao;LI Mingjuan;GUO Lei;LIU Desheng;LI Enyou(Department of Anesthesiology,The First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,China)
出处
《安徽医药》
CAS
2019年第2期225-231,共7页
Anhui Medical and Pharmaceutical Journal
