摘要
目的对直肠前切除术后发生吻合口漏风险进行评估。方法选取2005年3月至2009年8月在第二军医大学附属长征医院普外科接受直肠前切除的338名直肠癌患者为研究对象,所有患者均接受直肠全系膜切除,评估相关因素与吻合口漏的相关性。结果本研究的吻合口漏发生率为9.2%。通过单因素分析与多因素分析法发现年龄(OR:3.380,95%CI:1.346～8.489)、BMI(OR:11.828,95%CI:4.123～33.858)、肿瘤位置(OR:6.304,95%CI:162～18.382)、肠梗阻(OR:6.675,95%CI:2.164～20.594)是影响吻合口漏的独立因素。结论直肠前切除术后发生吻合口漏与患者的性别、年龄、BMI指数、肿瘤位置、肠梗阻等因素相关。对于男性、高龄、肥胖、低位直肠癌、合并肠梗阻等危险因素的患者而言,术后发生吻合口漏的风险将增高。
Objective To evaluate the risk of anastomotic leakage after anterior resection for rectal.Methods From March 2005 to August 2009,338 rectal cancer patients who underwent anterior resection of the Department of General Surgery in the Affiliated Changzheng Hospital of Second Military Medical University were selected as the subjects.All patients experienced a total mesorectal excision operation.Univariate and multivariate analysis were performed to determine risk factors for anastomotic leakage.Results The incidence of anastomotic leakage was 9.2%.Univariate analysis and multivariate analysis revealed that age(OR:3.380,95%CI:1.346~8.489),BMI(OR:11.828,95%CI:4.123~33.858),tumor location(OR:6.304,95%CI:162~18.382),and intestinal obstruction(OR:6.675,95%CI:2.164~20.594)were independent factors for anastomotic leakage.Conclusions The incidence of anastomotic leakage after anterior resection of rectum was related to the factors such as gender,age,BMI index,tumor location and intestinal obstruction.For patients with risk factors such as men,advanced age,obesity,low rectal cancer,intestinal obstruction,postoperative anastomotic leakage risk will increase.
作者
谢亚运
张言言
臧佳
胡志前
Xie Yayun;Zhang Yanyan;Zang Jia;Hu Zhiqian(Department of General Surgery,Affiliated Changzheng Hospital of The Second Military Medical University,Shanghai 200003,China)
出处
《中华结直肠疾病电子杂志》
2019年第1期38-41,共4页
Chinese Journal of Colorectal Diseases(Electronic Edition)
