摘要
目的探讨重庆市主城区在治人类免疫缺陷病毒(HIV)感染者/获得性免疫缺陷综合征(AIDS)患者服药依从性及其影响因素,为制定提高HIV/AIDS服药依从性措施提供科学依据。方法 2017年7月1日至8月31日采用问卷调查方式对重庆市主城区在治、前来领药的HIV/AIDS进行调查,并对其服药依从性及影响因素进行分析。结果共调查重庆市主城区在治HIV/AIDS 386例;年龄18～78岁,中位年龄33岁;男女性别比5. 7∶1;未婚者199例(51. 6%);以大专及以上文化程度为主[48.2%(186/386)]。90. 7%(350/386)服药依从性良好,年龄越大、工作年限越长是依从性的保护因素[优势比(OR)=0. 3、0. 2,95%可信区间(95%CI):0. 1～0. 8、0. 1～0. 9];接受治疗时间越长是依从性的危险因素(OR=3. 7,95%CI:1. 6～8. 7)。结论重庆市主城区在治(HIV/AIDS)服药依从性整体水平较高,为进一步巩固与提高,建议加强接受治疗时间较长的HIV/AIDS的服药依从性教育;加强无业人员和50岁以下人员的服药依从性教育和管理,强调对服药质量的监管。
Objective To investigate the medication compliance in the people with HIV infection and the patients with AIDS(PLWHA)in Chongqing urban area to provide a scientific evidence for formulating the measures enhancing HIV/AIDS medication compliance.Methods The survey was conducted on PLWHA with treatment and getting the medicine from the hospital from July 1 to August 31,2017 in Chongqing urban area by using the questionnaire method.The medication compliance and its influencing factors were analyzed.Results A total of 386 cases of PLWHA in Chongqing urban area were surveyed,with the age of 18-78 years old,the median age 33 years old;the male-to-female ratio was 5.7∶1,199 cases were unmarried(51.6%),the college degree or above was predominant[48.2%(186/386)].90.7%of respondents(350/386)had good medication compliance.The older age and long working years were the protective factors of compliance[odds ratio(OR)=0.3,0.2,95%confidence interval(CI):0.1-0.8,0.1-0.9];the longer time receiving treatment was the risk factor of compliance(OR=3.7,95%CI:1.6-8.7).Conclusion The medication compliance in HIV/AIDS with treatment is higher as a whole.It is suggested that the education on HIV/AIDS receiving long time treatment should be strengthened;the medication compliance education and management on the unemployed or people aged less than 50 years old should be strengthened and the supervision on medication quality should be strengthened.
作者
陈宗良
申涛
吴国辉
周超
韩梅
欧阳琳
卢戎戎
王璐
CHEN Zongliang;SHEN Tao;WU Guohui;ZHOU Chao;HAN Mei;OUYANG Lin;LU Rongrong;WANG Lu(Chongqing Municipal Center for Disease Control and Prevention,Chongqing 400042,China;Chinese Center for Disease Control and Prevention,Beijing 102206,China;China Field Epidemiology Training Program,Beijing 102206,China)
出处
《现代医药卫生》
2019年第2期192-194,198,共4页
Journal of Modern Medicine & Health
基金
重庆市卫生健康委员会医学科研项目(2017ZDXM001
2017MSXM001)
关键词
获得性免疫缺陷综合征/治疗
抗逆转录病毒治疗
高效
病人依从
问卷调查
重庆
Acquired immunodeficiency syndrome/therapy
Antiretroviral therapy,highly active
Patient compliance
Questionnaires
Chongqing
