摘要
目的研究甲状腺自身免疫抗体与丙型肝炎病毒感染的关系。方法选取2016年1月至2017年12月期间本校附院接收的甲状腺自身免疫抗体(thyroid autoimmune antibody,TAA)阳性患者150例(观察组)和甲状腺自身免疫抗体(TAA)阴性患者150例(对照组),对血清抗-HCV水平同TAA相关抗体的相关性进行分析。另外,再选择正常健康人群、丙型肝炎患者、慢性乙型肝炎患者各100例作为研究对象,对TpOAb水平与血清抗-HCV相关性进行分析。结果观察组和对照组的HCV感染率比较差异无统计学意义,观察组的抗-HCV水平明显更高(P<0.05);观察组高度阳性患者的血清抗-HCV水平高于中度、低度阳性患者(P<0.05);丙型肝炎组的TpOAb、TgAb阳性率比正常组、慢性乙型肝炎组高(P<0.05)。结论在临床中需对丙型肝炎患者加强甲状腺指标的监测,避免甲状腺自身免疫抗体的发生。
Objective To study the relationship between thyroid autoimmune antibodies and hepatitis C virus infection.Methods 150 patients with thyroid autoimmune antibody positive and 150 thyroid autoimmune antibody(TAA)negative patients received from the hospital from January 2016 to December 2017 were selected.Serum anti-HCV levels were compared between the two groups.The correlation with TAA-related antibodies was analyzed.In addition,normal healthy people,hepatitis C patients,and chronic hepatitis B patients were selected as subjects,100 in each group.The correlation between TpOAb levels and serum anti-HCV was analyzed.Results There was no significant difference in the HCV infection rate between the observation group and the control group.The anti-HCV level in the former group was significantly higher(P<0.05);serum anti-HCV was highly positive in the observation group.The positive rate of TpOAb and TgAb in hepatitis C group was higher than that in normal group and chronic hepatitis B group(P<0.05).Conclusion In the clinic,it is necessary to strengthen the monitoring of thyroid index in patients with hepatitis C and avoid the occurrence of thyroid autoimmune antibodies.
作者
刘锦龙
常江
任可
Liu Jinlong;Chang Jiang;Ren Ke(Department of Basic Medicine and Forensic Medicine,Baotou Medical College,Baotou,Inner Mongolia,014040,China)
出处
《当代医学》
2019年第5期26-27,共2页
Contemporary Medicine
基金
内蒙古自治区高等学校科学研究项目(NJZZ14254)
