摘要
目的探究无痛胃镜不同入镜时点丙泊酚联合舒芬太尼的静脉麻醉效果。方法 70例无痛胃镜检查患者,采用随机数字表法分为对照组与观察组,每组35例。对照组在患者睫毛反射消失后即刻入镜进行无痛胃镜检查,观察组在患者睫毛反射消失后30 s入镜进行无痛胃镜检查。比较两组患者不同时点心率(HR)、平均动脉压(MAP)和血氧饱和度(SpO2)情况;术后清醒时间以及丙泊酚用量;入镜过程中的不良反应发生情况。结果两组患者不同时点HR、MAP、SpO2比较差异无统计学意义(P>0.05);与本组诱导前(T0)时比较,两组患者入镜前(T1)时MAP均明显降低,差异具有统计学意义(P<0.05)。对照组患者术后清醒时间为(5.54±1.72)min,丙泊酚用量为(2.42±0.38)mg/kg;观察组患者术后清醒时间为(3.42±1.16)min,丙泊酚用量为(1.85±0.38)mg/kg;观察组术后清醒时间短于对照组,丙泊酚用量少于对照组,差异均具有统计学意义(P<0.05)。观察组患者不良反应发生率为5.71%,显著低于对照组的22.86%,差异具有统计学意义(P<0.05)。结论无痛胃镜检查在患者睫毛反射消失后30 s入镜检查可减少丙泊酚用量,缩短患者术后苏醒时间,减少不良反应,值得在临床推广使用。
Objective To discuss the intravenous anesthetic effect of propofol combined with sufentanil in painless gastroscopy at different time points. Methods A total of 70 painless gastroscopy patients were divided by random number table method into control group and observation group, with 35 cases in each group. The control group received painless gastroscopy immediately after the disappearance of eyelash reflex, and the observationgroup received painless gastroscopy 30 s after the disappearance of eyelash reflex. Comparison were made on heart rate(HR), mean arterial pressure(MAP) and blood oxygen saturation(SpO2) at different time points, postoperaive wake-up time and propofol dosage, and occurrence of adverse reactions during endoscopy between the two groups. Results Both groups had no statistically significant difference in HR, MAP, SpO2 at different time points(P>0.05). Compared with before induction(T0), both groups had obviously lower MAP before endoscopy(T1), and the difference was statistically significant(P<0.05). The control group had postoperaive wake-up time as(5.54± 1.72) min and propofol dosage as(2.42±0.38) mg/kg, while the observation group had postoperaive wake-up time as(3.42±1.16) min and propofol dosage as(1.85±0.38) mg/kg. The observation group had shorter postoperative wake-up time than the control group, and less propofol dosage than the control group. Their difference was statistically significant(P<0.05). The observation group had significantly lower incidence of adverse reactions as 5.71% than 22.86% in the control group, and the difference was statistically significant(P<0.05). Conclusion Painless gastroscopy 30 s after the disappearance of eyelash reflex can reduce the dosage of propofol, shorten the recovery time and reduce adverse reactions. It is worthy of clinical popularization and application.
作者
初秀
邵琳
聂晶鑫
CHU Xiu;SHAO Lin;NIE Jing-xin(Department of Anesthesia,Dalian Ganjingzi District People’s Hospital,Dalian 116033,China)
出处
《中国现代药物应用》
2019年第1期84-86,共3页
Chinese Journal of Modern Drug Application
关键词
无痛胃镜
丙泊酚
舒芬太尼
麻醉效果
Painless gastroscopy
Propofol
Sufentanil
Anesthetic effect
