摘要
肝(窦)前型非肝硬化性门静脉高压症(NCPH)是一组以门静脉高压症为突出表现的血管异质性疾病,病因复杂。与肝硬化门静脉高压症相比,NCPH患者肝功能基本正常,肝静脉压力梯度正常或轻度增加,预后较好,极易误诊为不明原因肝硬化门静脉高压症,肝脏病理是诊断"金标准"。目前,非选择性β受体阻滞剂及内镜是NCPH的主要治疗方法,但是缺乏前瞻性多中心、大样本、高质量的临床证据。
Pre-hepatic( sinusoidal) non-cirrhotic portal hypertension is a group of vascular heterogeneous diseases with portal hypertension as the prominent manifestation and has a complex etiology. Compared with the patients with cirrhotic portal hypertension,the patients with pre-hepatic( sinusoidal) non-cirrhotic portal hypertension have normal liver functions,normal or a mild increase in hepatic venous pressure gradient,and better prognosis. Pre-hepatic( sinusoidal) non-cirrhotic portal hypertension may easily be misdiagnosed as unexplained cirrhotic portal hypertension,and liver pathology is the gold standard for diagnosis. Non-selective β-receptor blockers and endoscopy are major therapies for this disease,but there is a lack of high-quality clinical evidence from large-scale prospective multicenter studies.
作者
徐航飞
丁惠国
XU Hangfei;DING Huiguo(Center of Hepatic and Digestive Diseases,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2019年第1期13-17,共5页
Journal of Clinical Hepatology
基金
北京市医院管理局扬帆计划(ZYLX201610)
登峰计划(DFL20151602)
关键词
高血压
门静脉
诊断
治疗
hypertension,portal
diagnosis
therapy
