摘要
目的研究原发性高血压患者脂蛋白a和胱抑素C血清水平与高血压分级的相关性,探讨脂蛋白a及胱抑素C在高血压患者病情严重程度评估的临床应用价值。方法将342例原发性高血压患者根据高血压分级标准分为低危组56例,中危组78例,高危组101例,极高危组107例,比较各组原发性高血压患者脂蛋白a和胱抑素C血清水平的差异,并研究脂蛋白a和胱抑素C血清水平与高血压分级的相关性。结果脂蛋白a与胱抑素C血清水平在低危组、中危组、高危组及极高危组依次升高,任意组间比较,差异均有统计学意义(P<0.05),脂蛋白a和胱抑素C血清水平与高血压分级均呈正相关,差异均有统计学意义(r=0.617、0.669,P<0.05)。结论脂蛋白a、胱抑素C血清水平的监测有助于了解原发性高血压患者病情的危重程度,对高血压的防治具有重要的临床意义。
Objective To study the relationship between hypertension and lipoprotein a serum cystatin C level and the grade of hypertension,investigate lipoprotein A and cystatin C in patients with hypertension disease severity assessment of the clinical value.Methods 342 cases of primary hypertension patients according to the grading criteria of hypertension were divided into low-risk group 56 cases,78 cases of risk group,high risk group of 101 cases,107 cases of high risk group,the differences were compared in patients with essential hypertension and lipoprotein a serum levels of cystatin C,and lipoprotein associated a and cystatin C in blood clear the level and the grade of hypertension.Results the serum lipoprotein A and serum cystatin C levels were significantly higher in the low risk group,medium risk group,high risk group and high risk group,any differences between groups were statistically significant(P<0.05),apolipoprotein A(r=0.617)and cystatin C(r=0.669)serum levels and hypertension grade were statistically significant(P<0.05).Conclusion the monitoring of lipoprotein A and cystatin c serum concentration is helpful for clinical understanding of the critical condition of patients with essential hypertension,and has important clinical significance for the prevention and treatment of hypertension.
作者
侯义福
陈莹莹
HOU Yifu;CHEN Yingying(Department of Clinical Laboratory,Lu'an Hospital of Traditional Chinese Medicine,Lu'an,Anhui 237000,China)
出处
《国际检验医学杂志》
CAS
2019年第1期92-94,共3页
International Journal of Laboratory Medicine
关键词
高血压分类
脂蛋白A
抑素类
实验室技术和方法
hypertension classification
lipoprotein a
chalones
laboratory techniques and procedures
