摘要
目的针对颅脑电阻抗断层成像临床应用中,由于测量电极与皮肤之间的接触状态不断变化导致接触阻抗和电极极化电位的改变,从而引起原始电压测量信号变化的问题。本文提出了一种效率高、性能出色的干扰预处理方法。方法利用对照实验分析了临床与理想环境下的数据差异,发现临床环境下的干扰普遍符合特定的模式,提出了线性噪声模型。为了恢复原始电压测量信号,本文设计了具有数据正则项的目标函数并利用梯度下降法进行优化。结果临床实验结果表明该算法可以有效地滤除干扰影响。结论相比于处理解调后的数据,进行原始电压测量信号干扰预处理可以有效地从根源控制数据质量,进而更好地辅助大量临床数据的分析工作。
Objective In the clinical application of brain electrical impedance tomography,the change of contact state between the measuring electrode and the skin,the contact impedance and the polarization potential of the electrode change often cause the change of the original voltage measurement signal.In this paper,an efficiency,high-precision interference pre-processing method was proposed to improve the signal quality.Methods In response to this phenomenon,an interference pretreatment method with high efficiency and excellent performance was proposed.The control experiment was used to analyze the difference of data distribution between clinical and ideal environments.It was found that the interference in the clinical environment generally conformed to the specific model,and a differentiable noise model was proposed.In order to restore the original voltage measurement signal,the objective function with data regular term was designed and optimized by gradient descent method.Results The clinical experiment results showed that the algorithm could effectively filter out the interference effect.Conclusion Compared with the processed data,the original voltage measurement signal interference preprocessing can effectively control the data quality from the root source,and thus better assist the analysis of a large number of clinical data.
作者
曾玉姗
徐灿华
马航
李蔚琛
付峰
黄力宇
史学涛
夏军营
ZENG Yushan;XU Canhua;MA Hang;LI Weichen;FU Feng;HUANG Liyu;SHI Xuetao;XIA Junying(School of Life Science and Technology,Xidian University,Xi’an Shaanxi 710126,China;College of Biomedical Engineering,Military Medical University of Air Force,Xi’an Shaanxi 710032,China)
出处
《中国医疗设备》
2019年第1期10-13,共4页
China Medical Devices
基金
军队重大项目(AWS14C006)
陕西省社会发展科技攻关项目(2016SF-258)
关键词
电阻抗断层成像
原始电压测量信号
目标函数
梯度下降法
electrical impedance tomography
original voltage measurement signal
objective function
gradient descent
