摘要
目的探讨NLR、RDW和PCT水平与未足月胎膜早破(PPROM)合并宫内感染关系,分析相关危险因素,并建立预测模型。方法选择61例PPROM组,31例PROM组和30例正常对照组,检测PCT、RDW和NLR;运用SPSS 13.0软件进行统计分析。结果 (1)PPROM组在宫内感染、RDW、PCT、NLR高于PROM组、正常对照组,差异有统计学意义(P <0.05);(2)Logistic回归分析获得PCT、NLR及RDW是影响PPROM合并宫内感染危险因素,NLR相对危险度为26.027;并获得其预测回归模型。此外,NLR与RDW、PCT呈正相关;(3)ROC曲线显示,NLR预测PPROM合并宫内感染危险因子界点值为3.588,曲线下面积为0.988,约登指数为0.762;(4)破膜时间与PPROM是否合并宫内感染无相关性。结论 NLR超过界点值3.588时,可增加PPROM合并宫内感染早期发病风险。
Objective To investigate the relationship between the level of NLR,RDW and PCT in the PPROM with intrauterine infection,to analyze its related risk factors and to establish its prediction model.Methods PCT,RDW and NLR were detected in 61 cases of PPROM,31 cases of PROM and 30 cases of normal con-trol group. SPSS 13.0 software was used for statistical analysis.Results Firstly,the intrauterine infection,RDW,PCT and NLR in PPROM group were higher than those in PROM group and normal control group and the difference was statistically significant(P < 0.05). Secondly,logistic regression analysis showed that PCT,NLR and RDWwere the risk factors of PPROM complicated with intrauterine infection,and the relative risk of NLR was 26.027.In addition,NLR is positively correlated with RDW and PCT. Thirdly,ROC curve showed that NLR predictedPPROM with intrauterine infection risk factors threshold value of 3.588,AUC was 0.988,Yorden index was 0.762.Lastly,there was no correlation between the time of rupture and whether PPROM was combined with intrauterine infection.Conclusions When NLR exceeds 3.588 of the cutoff point,it can increase the early risk of PPROM combined with intrauterine infection.
作者
黄艳
周杜娟
徐雁
夏宏林
HUANG Yan;ZHOU Dujuan;XU Yan;XIA Honglin(Department of Gynaecology and Obstetrics,Suzhou Municipal Hospital affiliated to Anhui Medical University,Suzhou 234000,China)
出处
《实用医学杂志》
CAS
北大核心
2018年第24期4141-4145,共5页
The Journal of Practical Medicine
关键词
PPROM
宫内感染
预测
PCT
NLR
RDW
preterm premature rupture of membranes
intrauterine infection
prediction
PCT
NLR
RDW
