摘要
目的探讨自拟凉血止痒方加减配合中波紫外线治疗急性期血热证寻常型银屑病的临床疗效。方法选取我院(2015年1月—2017年1月)收治的86例急性期血热证寻常型银屑病患者为研究对象,根据治疗方法不同将本组患者分为两组,两组患者均给予窄谱中波紫外线(NB-UVB)治疗,观察组在此基础上再给予自拟凉血止痒方加减治疗,对比两组患者临床疗效和治疗前后银屑病严重程度以及血清干扰素-γ(IFN-γ)、白细胞介素-2(IL-2)水平。结果观察组总有效率97.67%,对照组总有效率81.40%,观察组临床疗效明显高于对照组,差异具有统计学意义(χ2=14.125 8,P <0.05)。观察组PASI评分、血清IFN-γ、IL-2水平明显低于对照组,差异具有统计学意义(P<0.05)。结论急性期血热证寻常型银屑病采用NB-UVB联合中药凉血止痒方剂治疗效果显著。
Objective To investigate the clinical efficacy of self cooling and blood stasis relieving itching prescription combined with UVB in the treatment of psoriasis vulgaris in acute phase of blood heat syndrome.Methods86cases of psoriasis vulgaris in acute period of blood heat syndrome in our hospital(from January2015to January2017)were selected as the research object.According to the different treatment methods,the patients were divided into two groups,the two groups were given NB-UVB treatment.On the basis of this,the observation group was given the treatment of self-designed cold blood antipruritic prescription,and the two groups were compared.The clinical efficacy,psoriasis and serum levels of interferon gamma(IFN-gamma)and interleukin-2(IL-2)before and after treatment were observed.Results The total effective rate of the observation group was97.67%,the total effective rate of the control group was81.40%,and the clinical effect of the observation group was significantly higher than that of the control group.The difference was statistically significant(χ^2=14.1258,P<0.05).The PASI score,serum IFNgamma and IL-2levels in the observation group were significantly lower than those in the control group(P<0.05).Conclusion The treatment of psoriasis vulgaris in acute phase of blood heat syndrome with NB-UVB combined with Chinese medicine cooling blood and relieving itching is effective.
作者
郑莉
ZHENG Li(Department of Dermatology,Xiangyang Traditional Chinese Medicine Hospital,Xiangyang Hubei 441000,China)
出处
《中国继续医学教育》
2019年第1期135-137,共3页
China Continuing Medical Education
关键词
凉血止痒方
中波
紫外线
急性期
血热证
寻常型银屑病
cooling blood and relieving itching prescription
medium wave
ultraviolet
acute phase
blood heat syndrome
psoriasis vulgaris
